Industrial application of environmentally hazardous substances have led to contamination of important groundwater aquifers worldwide. Decreasing groundwater quality poses risks to human health, water and food supply, and biodiversity. In Europe, a total of 2.8 million contaminated sites was estimated in 2017 (Pérez & Eugenio, 2018), while in the US, the legal authorities had to manage up to 1.3 million contaminated sites in 2017 (U.S. Environmental Protection Agency, 2017). In Denmark, groundwater is the primary source for drinking water and >36,000 contaminated sites were registered in 2018 (Olsen et al., 2020). Source zone remediation by excavation is a typical, but expensive method that can lead to a significant carbon footprint (Søndergaard et al., 2018). In many cases, the source zone contamination depletes and creates a contamination plume in the groundwater aquifer (Fjordbøge et al., 2017;Murray et al., 2019;Steelman et al., 2020).The development of cost-effective in situ remediation technologies, where contaminant plumes are directly treated in the groundwater, is a high priority (