Temporal relationships of GH, IGF-I and fructosamine concentrations in pregnant Spanish Purebred mares: A substantial contribution from the hormonal standpoint

Polymorphism of insulin-like growth factor 1 gene and its relationship with reproductive performances and milk yield in Sarda dairy sheep

“…Also, in other animals’ species a positive effect of some polymorphisms of the IGF-I gene on reproductive activity has been found and many times this effect has been linked to the type of animal management ( Hax et al., 2017 ). The important role of IGF-I hormone has been recognized in several reproductive stages, in fact, the higher levels of this hormone in pregnancy are necessary for fetal development and in postpartum favor the recovery of ovarian function ( Kawashima et al., 2006 ; Satue, Marcilla, Medica, Cravana & Fazio, 2018 ). In addition, in bovine granulose cell, FSH acts in synergy with IGF-I to increase cell number and aromatase expression ( Silva, Figueiredo & van den Hurk, 2009 ).…”