Temporal trends in cardiovascular outcomes and costs among patients with type 2 diabetes

Williams, Brent A.; Rajpura, Jigar; Paprocki, Yurek; Kumar, Neela; Voyce, Stephen J.; Brady, Jonathan P.; Chang, Alexander R.

doi:10.1016/j.ahj.2023.07.012

Cited by 3 publications

(1 citation statement)

References 49 publications

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“…With over 536 million individuals affected globally as of 2021 [ 3 ], T2DM poses a significant health challenge, projected to impact 783 million by 2045. The disease contributes to severe health complications [ 4 – 6 ] and a considerable burden on healthcare systems [ 7 ].…”

Section: Introductionmentioning

confidence: 99%

The effects of major dietary patterns on patients with type 2 diabetes: Protocol for a systematic review and network meta-analysis

Chen,

Wang,

et al. 2024

PLoS ONE

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Background Type 2 diabetes mellitus (T2DM) represents a significant worldwide health issue, experiencing an increasing incidence rate. Effective dietary strategies are vital for T2DM management, but the optimal dietary patterns remain debated due to inconsistent research outcomes and single-outcome reporting. Network Meta-Analysis (NMA) provides a powerful approach for integrating data from randomized controlled trials (RCTs), enabling a detailed evaluation of the impact of different dietary patterns. This document presents our strategy for a systematic review and network meta-analysis, aimed at assessing the influence of key dietary patterns on glycemic control, lipid profiles, and weight management in individuals with Type 2 Diabetes Mellitus (T2DM). Materials and methods Adhering to the Preferred Reporting Items for Systematic Reviews and Meta-Analysis Protocols (PRISMA-P) and network meta-analyses guidelines, we conducted a comprehensive search of PubMed, EMBASE, and the Cochrane Library, without language or date restrictions. Our objective is to assess the efficacy of various dietary interventions in managing Type 2 Diabetes Mellitus (T2DM). We used standardized mean differences for pairwise comparisons and a Bayesian framework for ranking interventions via Surface Under the Cumulative Ranking Curve (SUCRA). Key analyses include heterogeneity, transitivity, and sensitivity assessments, along with quality and risk evaluations using the Cochrane Collaboration’s tool and the Grading of Recommendations, Assessment, Development, and Evaluation (GRADE) system. Ethics and dissemination This systematic review and network meta-analysis involve aggregate data from previous trials, obviating the need for additional ethical approval. The search strategy will be executed starting October 2023, with all searches completed by December 2023, to encompass the most current studies available. Findings will be shared through academic conferences and peer-reviewed journals focused on diabetes care and nutrition. Trial registration PROSPERO registration number CRD42023465791.

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Section: Introductionmentioning

confidence: 99%

The effects of major dietary patterns on patients with type 2 diabetes: Protocol for a systematic review and network meta-analysis

Chen,

Wang,

et al. 2024

PLoS ONE

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Addressing disparities in the long-term mortality risk in individuals with non-ST segment myocardial infarction (NSTEMI) by diabetes mellitus status: a nationwide cohort study

Cole,

Weight,

Misra

et al. 2024

Diabetologia

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Aims/hypothesis The aim of this study was to investigate how diabetes mellitus affects longer term outcomes in individuals presenting to hospital with non-ST segment elevation myocardial infarction (NSTEMI). Methods We analysed data from 456,376 adults hospitalised between January 2005 and March 2019 with NSTEMI from the UK Myocardial Ischaemia National Audit Project (MINAP) registry, linked with Office for National Statistics death reporting. We compared outcomes and quality of care by diabetes status. Results Individuals with diabetes were older (median age 74 vs 73 years), were more often of Asian ethnicity (13% vs 4%) and underwent revascularisation (percutaneous coronary intervention or coronary artery bypass graft surgery) (38% vs 40%) less frequently than those without diabetes. The mortality risk for those with diabetes compared with those without was significantly higher at 30 days (HR 1.19, 95% CI 1.15, 1.23), 1 year (HR 1.28, 95% CI 1.26, 1.31), 5 years (HR 1.36, 95% CI 1.34, 1.38) and 10 years (HR 1.39, 95% CI 1.36, 1.42). In individuals with diabetes, higher quality inpatient care, assessed by opportunity-based quality indicator (OBQI) score category (‘poor’, ‘fair’, ‘good’ or ‘excellent’), was associated with lower mortality rates compared with poor care (good: HR 0.74, 95% CI 0.73, 0.76; excellent: HR 0.69, 95% CI 0.68, 0.71). In addition, compared with poor care, excellent care in the diabetes group was associated with the lowest mortality rates in the diet-treated and insulin-treated subgroups (diet-treated: HR 0.64, 95% CI 0.61, 0.68; insulin-treated: HR 0.69, CI 0.66, 0.72). Conclusion/interpretation Individuals with diabetes experience disparities during inpatient care following NSTEMI. They have a higher risk of long-term mortality than those without diabetes, and higher quality inpatient care may lead to better long-term survival. Graphical Abstract

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Incidence trends in ischaemic and non-ischaemic heart failure in people with and without type 2 diabetes, 2000–2019: An observational study in England

Panchal,

Lawson,

Shabnam

et al. 2024

Diabetes Research and Clinical Practice

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Temporal trends in cardiovascular outcomes and costs among patients with type 2 diabetes

Cited by 3 publications

References 49 publications

The effects of major dietary patterns on patients with type 2 diabetes: Protocol for a systematic review and network meta-analysis

The effects of major dietary patterns on patients with type 2 diabetes: Protocol for a systematic review and network meta-analysis

Addressing disparities in the long-term mortality risk in individuals with non-ST segment myocardial infarction (NSTEMI) by diabetes mellitus status: a nationwide cohort study

Incidence trends in ischaemic and non-ischaemic heart failure in people with and without type 2 diabetes, 2000–2019: An observational study in England

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