Temporal trends in hospitalization and in-hospital mortality rates due to heart failure by age and sex in Spain (2003-2018)

Sánchez, Manuel Anguita; Palomas, Juan Luis Bonilla; Márquez, María García; Sobrino, José Luis Bernal; Somoza, Francisco Javier Elola; Ortuño, Francisco Marín

doi:10.1016/j.rec.2021.04.017

Cited by 4 publications

(2 citation statements)

References 5 publications

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“…Previous epidemiological studies, such as BADAPIC in 2004 [6] and PRICE in 2008 [7] , showed a mean age of around 65 years, although most patients were over 70 years. This shows that the prevalence of the disease increases with age, being the leading cause of hospital admission in those over 65 years [4] and, especially, in those over 80 years. [5] The prevalence of HF appears to be higher in women.…”

Section: Discussionmentioning

confidence: 86%

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Characteristics and in-hospital mortality of elderly patients with heart failure in Spanish hospitals

Esteban‐Fernández¹,

Anguita‐Sánchez²,

Bonilla-Palomas³

et al. 2023

Journal of Geriatric Cardiology

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BACKGROUNDThe prevalence of heart failure (HF) increases with age, and it is one of the leading causes of hospitalization and death in older patients. However, there are little data on in-hospital mortality in patients with HF ≥ 75 years in Spain.METHODS A retrospective analysis of the Spanish Minimum Basic Data Set was performed, including all HF episodes discharged from public hospitals in Spain between 2016 and 2019. Coding was performed using the International Classification of Diseases, 10 th Revision. Patients ≥ 75 years with HF as the principal diagnosis were selected. We calculated: (1) the crude in-hospital mortality rate and its distribution according to age and sex; (2) the risk-standardized in-hospital mortality ratio; and (3) the association between in-hospital mortality and the availability of an intensive cardiac care unit (ICCU) in the hospital. RESULTSWe included 354,792 HF episodes of patients over 75 years. The mean age was 85.2 ± 5.5 years, and 59.2% of patients were women. The most frequent comorbidities were renal failure (46.1%), diabetes mellitus (35.5%), valvular disease (33.9%), cardiorespiratory failure (29.8%), and hypertension (26.9%). In-hospital mortality was 12.7%, and increased with age [odds ratio (OR) = 1.07, 95% CI: 1.

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Section: Discussionmentioning

confidence: 86%

“…[1] The incidence of HF increases with age and it is estimated that 20% of those over 75 years have HF. [2] Moreover, it is the most frequent cause of hospitalization over 65 years, [3,4] especially in those over 80 years. [5] The average age of patients with HF in Spain is around 65 years, although 40% of those are over 70 years.…”

mentioning

confidence: 99%

Characteristics and in-hospital mortality of elderly patients with heart failure in Spanish hospitals

Esteban‐Fernández¹,

Anguita‐Sánchez²,

Bonilla-Palomas³

et al. 2023

Journal of Geriatric Cardiology

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A decade of hospitalizations for hyperthyroidism in the US

Salim

DeHart

El-Amir

et al. 2022

Baylor University Medical Center Proceedings

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Prevalence, Characteristics, Management and Outcomes of Patients with Heart Failure with Preserved, Mildly Reduced, and Reduced Ejection Fraction in Spain

Cervantes

Palacios

Varela

et al. 2022

JCM

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Objective: To estimate the prevalence, incidence, and describe the characteristics and management of patients with heart failure with preserved (HFpEF), mildly reduced (HFmrEF), and reduced ejection fraction (HFrEF) in Spain. Methods: Adults with ≥1 inpatient or outpatient HF diagnosis between 1 January 2013 and 30 September 2019 were identified through the BIG-PAC database. Annual incidence and prevalence by EF phenotype were estimated. Characteristics by EF phenotype were described in the 2016 and 2019 HF prevalent cohorts and outcomes in the 2016 HF prevalent cohort. Results: Overall, HF incidence and prevalence were 0.32/100 person-years and 2.34%, respectively, but increased every year. In 2019, 49.3% had HFrEF, 38.1% had HFpEF, and 4.3% had HFmrEF (in 8.3%, EF was not available). Compared with HFrEF, patients with HFpEF were largely female, older, and had more atrial fibrillation but less atherosclerotic cardiovascular disease. Among patients with HFrEF, 76.3% were taking renin-angiotensin system inhibitors, 69.5% beta-blockers, 36.8% aldosterone antagonists, 12.5% sacubitril/valsartan and 6.7% SGLT2 inhibitors. Patients with HFpEF and HFmrEF took fewer HF drugs compared to HFrEF. Overall, the event rates of HF hospitalization were 231.6/1000 person-years, which is more common in HFrEF patients. No clinically relevant differences were found in patients with HFpEF, regardless EF (50- < 60% vs. ≥60%). Conclusions: >2% of patients have HF, of which around 50% have HFrEF and 40% have HFpEF. The prevalence of HF is increasing over time. Clinical characteristics by EF phenotype are consistent with previous studies. The risk of outcomes, particularly HF hospitalization, remains high, likely related to insufficient HF treatment.

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Temporal trends in hospitalization and in-hospital mortality rates due to heart failure by age and sex in Spain (2003-2018)

Cited by 4 publications

References 5 publications

Characteristics and in-hospital mortality of elderly patients with heart failure in Spanish hospitals

Characteristics and in-hospital mortality of elderly patients with heart failure in Spanish hospitals

A decade of hospitalizations for hyperthyroidism in the US

Prevalence, Characteristics, Management and Outcomes of Patients with Heart Failure with Preserved, Mildly Reduced, and Reduced Ejection Fraction in Spain

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