Temporary Abolition of Pain in Man

Wall, Patrick D.; Sweet, William H.

doi:10.1126/science.155.3758.108

Cited by 885 publications

(311 citation statements)

References 3 publications

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“…DISCUSSION The results in general support a gating meehanism interpretation of pain pereeption. In addition, the small but significant reduction in estimates of experimentally induced pain lends support to the clinical observations reported by both Wall & Sweet (1967) and Meyer & Fields (in press). One should,however, interpret the data of the present study with a note of caution.…”

supporting

confidence: 69%

The aftereffects of peripheral nerve stimulation: Change in psychophysical judgments and autonomic reactions during the scaling of cutaneous pain

1972

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Psychophysical estimates of pain intensity, experimentally induced in the index and third fingers with a dolorimeter, were compared for three "normal" human Os before and after low-level electrical stimulation of the median nerve. Estimates of high, but not low, intensity thermal stimuli decreased after peripheral nerve stimulation. Psychophysiological indices mirrored the psychophysical data. Both the number and amplitude of the galvanic skin responses to the stimuli decreased after nerve stimulation.

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supporting

confidence: 69%

The aftereffects of peripheral nerve stimulation: Change in psychophysical judgments and autonomic reactions during the scaling of cutaneous pain

1972

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“…When Wall and Sweet 19 tried to find a new approach to suppress neuropathic pain, they inserted an electrode into their own infraorbital foramina and obtained a decrease in pain perception during the entire episode of electrical stimulation. 23 Moreover, in the first article dedicated to the idea of PNS with implantable devices (even before spinal cord stimulation was introduced), 19 one of the eight patients with neuropathic pain presented with severe facial pain, and in this patient an electrode was inserted deep into the infraorbital foramen. The stimulation resulted in lasting pain suppression as long as the stimulator was on.…”

mentioning

confidence: 99%

Trigeminal and occipital peripheral nerve stimulation for craniofacial pain: a single-institution experience and review of the literature

Kv¹,

Me²,

N³

et al. 2006

FOC

179

120

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Object Treatment of chronic neuropathic pain in the region of the head and face presents a challenge for pain specialists; patients who do not respond to conventional treatment modalities usually continue to suffer from pain due to the lack of reliable medical and surgical approaches. Peripheral nerve stimulation (PNS) has been used to treat neuropathic pain for many decades, but only recently has it been applied systematically to the craniofacial region. To advance the study of this treatment option, the authors present their initial experience with this approach, summarize published data on the use of PNS in treatment of craniofacial pain, and discuss some technical details of the craniofacial PNS procedure. Methods A review of prospectively collected data in 30 patients who underwent PNS surgery for craniofacial pain was performed. The pain location, duration, cause, and previous treatments were analyzed, along with the surgical details, initial and long-term results, complications, and repeated operations. Stimulated nerves in this group included supraorbital (seven patients), infraorbital (six), and occipital (21); in 19 patients more than one nerve was stimulated. Twenty-two patients proceeded with implantation of a permanent system after the trial. Of these, at the time of the latest evaluation (mean follow-up duration 35 months), in two patients the devices had been removed because of pain improvement over time, in three the devices were removed due to loss of effectiveness (two cases) or late infection (one), and the rest are enjoying either complete (15 patients) or partial (two patients) pain relief. Three patients underwent repeated operation due to lead erosion, infection, or migration. Conclusions Peripheral nerve stimulation appears to be a safe and effective approach in the treatment of craniofacial neuropathic pain. The growing body of literature supports a wider acceptance of this approach in the field of pain surgery.

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“…Desarrolló junto a Mauro técnicas de estimulación cerebral en animales. Este trabajo fue publicado en 1950 y permitió junto a Sweet desarrollar las técnicas de estimulación trascutánea que fue la base para la estimulación de los cordones posteriores en el tratamiento del dolor crónico (16). la primera serie de pacientes tratados con estos dispositivos fue publicado por Sweet y Wall en 1967. los trabajos realizados por el Dr. Wall en esta época sobre la fisiología de la médula espinal comenzaron a dimensionar su nombre en el contexto científico, no solo de Estados Unidos.…”

Section: Patrick David Wall (1925-2001)unclassified

Ronald Melzack and Patrick Wall. La teoría de la compuerta: más allá del concepto científico dos universos científicos dedicados al entendimiento del dolor

González

2013

Rev. Soc. Esp. Dolor

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La teoría de la compuerta. Más allá del concepto cientí-fico dos universos científicos dedicados al entendimiento del dolor. Rev Soc Esp Dolor 2013; 20(4): 191-202. ABSTRACTThe quest to acquire knowledge and understanding of pain has had crucial moments in which the evolution of the process has been dramatically changed. These moments have been revelations that have opened the path to rethinking previously accepted knowledge and created new horizons of research, understanding and treatment. When Melzack and Wall first described what would come to be known as the "Gate Control theory" they were able not only to clarify basic aspects of pain development but to lead the way to further basic and clinical research studies. They psychological aspects, the clinical basis and the structural anatomical and physiological components created one of the most complete theories in medical sciences and the ground for the basic management of pain. It has been fifty years since the original article was published in Science magazine (Pain Mechanism: a new theory. A gate control system modulates sensory input from the skin before it evokes pain perception and response. Ronald Melzack and Patrick Wall. Science. November 19, 1965 volume 150, number 3699). It has been recognized even until today as the most cited reference in medical journals in the past 50 years. The paper was written during a very particular moment in scientific history and the context of two very different lives, which illustrates the incredible process that leads to scientific development. The analysis of what this paper has symbolized to pain science must be done not only from a purely scientific view point but from a human one as well. RESUMENLa evolución histórica para el conocimiento del dolor ha tenido momentos cruciales en los que el curso evolutivo se modificó. Esos momentos son situaciones relevantes que cambiaron los conceptos previamente aceptados y abrieron nuevos horizontes de investigación, de entendimiento y de tratamiento. Cuando Melzack y Wall desarrollaron la "Teoría de la Compuerta" lograron aclarar fenómenos básicos del entendimiento del dolor pero igualmente abrieron múltiples tópicos de futuras investigaciones básicas y clínicas. Dieron sustento, con su teoría, a múltiples tratamientos del dolor que son la base de procedimientos que en la actualidad realizamos. Los aspectos psicológicos, el componente clínico y la base estructural anatomofisiológica fueron poco a poco conformando una de las teorías más completas de la ciencia médica y por supuesto principio básico para el mejor tratamiento del dolor. Son 50 años que se cumplen de la publicación de aquel artí-culo en la revista Science (Pain Mechanism: a new theory. A gate control system modulates sensory input from the skin before it evoques pain perception and response. Ronald Melzack and Patrick Wall. Science. 19 november 1965, volumen 150, number 3699), el cual ha sido reconocido hasta la actualidad como la referencia bibliográfica más utilizada en la ciencia médica en los últimos 50 años....

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Temporary Abolition of Pain in Man

Cited by 885 publications

References 3 publications

The aftereffects of peripheral nerve stimulation: Change in psychophysical judgments and autonomic reactions during the scaling of cutaneous pain

The aftereffects of peripheral nerve stimulation: Change in psychophysical judgments and autonomic reactions during the scaling of cutaneous pain

Trigeminal and occipital peripheral nerve stimulation for craniofacial pain: a single-institution experience and review of the literature

Ronald Melzack and Patrick Wall. La teoría de la compuerta: más allá del concepto científico dos universos científicos dedicados al entendimiento del dolor

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