“…Also, although degenerative TMJ changes were more frequently associated with skeletal jaw discrepancies, wide variations were reported in cases with relatively similar malocclusions [16]. TMJ degenerative changes could be multifactorial and might be caused by a wide variety of possible factors: genetic factors [42], gender, dietary loading [43], tooth loss, tooth attrition, occlusal disturbances, TMJ overloading, congenital abnormality (congenital condyle dysplasia), inflammation [44], trauma, ageing [15], bruxism, unilateral chewing, and internal derangement [23,28,29,[45][46][47][48].…”