2021
DOI: 10.1111/ijcp.13914
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Ten cases of aquagenic syringeal acrokeratoderma revealed during the COVID‐19 outbreak

Abstract: Aquagenic syringeal acrokeratoderma (ASA) is a rare, acquired disease affecting predominantly young women. It is characterised by the development of hypopigmented, translucent, flat-topped, oedematous papules and plaques that form hyperwrinkling or keratoderma. 1 It occurs after 3-5 minutes of contact with water and resolves when the hand dries. 1 Although its aetiology is not known

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Cited by 6 publications
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“…It is characterised clinically by flat-topped, pitted or translucent papules with pebbly or white, conspicuous eccrine pores that seem macerated and form hyperwrinkling or keratoderma occurring 3–5 minutes after contact with water and subside on drying. [ 3 8 ] The “hand in the bucket” sign is a diagnostic sign that occurs when skin lesions become more prominent after being submerged in water. [ 7 9 ] Skin biopsy of these lesions shows spongiotic alterations in the stratum corneum, orthohyperkeratosis with acanthosis, dilatation of the eccrine acrosyringia and crenulated appearance of the luminal cells of the secretory eccrine coils.…”
mentioning
confidence: 99%
“…It is characterised clinically by flat-topped, pitted or translucent papules with pebbly or white, conspicuous eccrine pores that seem macerated and form hyperwrinkling or keratoderma occurring 3–5 minutes after contact with water and subside on drying. [ 3 8 ] The “hand in the bucket” sign is a diagnostic sign that occurs when skin lesions become more prominent after being submerged in water. [ 7 9 ] Skin biopsy of these lesions shows spongiotic alterations in the stratum corneum, orthohyperkeratosis with acanthosis, dilatation of the eccrine acrosyringia and crenulated appearance of the luminal cells of the secretory eccrine coils.…”
mentioning
confidence: 99%