Ten-Year Changes in Television Viewing and Physical Activity Are Associated With Concurrent 10-Year Change in Pericardial Adiposity: The Coronary Artery Risk Development in Young Adults Study

Abstract

Background: Longitudinal association of television (TV) viewing and moderate- to vigorous-intensity physical activity (MVPA) with pericardial adipose tissue (PAT) is unclear. Methods: We studied Coronary Artery Risk Development in Young Adults Study participants transitioning from early to middle age at Coronary Artery Risk Development in Young Adults (CARDIA) exam years 15 (2000–2001; N = 1975, mean age = 40.4, 55.4% women, 45.3% Black) and 25 (2010–2011). TV viewing (in hours per day) and MVPA (in exercise units) were measured using a self-report questionnaire. PAT volume (in milliliters) was measured using computed tomography. Multivariable linear regression was used to examine the associations of tertiles of 10-year change (years 25–15) in TV viewing and MVPA with a concurrent change in PAT with adjustments for covariates. Results: Participants in the highest tertile of 10-year increase in TV viewing had a greater increase in PAT (β = 2.96 mL, P < .01). Participants in both middle (β = −3.93 mL, P < .01) and highest (β = −6.22 mL, P < .01) tertiles of 10-year changes in MVPA had smaller mean increases in PAT over 10 years when compared with the lowest tertile in fully adjusted models. Conclusions: Reducing or maintaining early-midlife levels of TV viewing and increasing MVPA may be associated with less PAT accumulation with age.

Implications of metabolism on multi‐systems healthy aging across the lifespan

“…Methods for adjudication of each of the endpoints in CARDIA are provided in references in Table 1 . In brief, physical activity was quantified via questionnaire (Jacobs Jr. et al., 1989 ), and methods for adjudication of computed tomographic indices of adiposity and muscle quantity (Granados et al., 2019 ; Oh et al., 2022 ), fitness (Shah et al., 2022 ), cardiac phenotypes (Shah et al., 2016 ), and neurocognitive assessments (Reis et al., 2013 ) have been previously described.…”

“…CARDIA participants have been longitudinally followed with repeated assessments for a variety of exposures and outcomes, including anthropometry, cardiovascular risk factors, and incident cancer, cardiovascular disease, and mortality (Friedman et al, 1988) Methods for adjudication of each of the endpoints in CARDIA are provided in references in Table 1. In brief, physical activity was quantified via questionnaire (Jacobs Jr. et al, 1989), and methods for adjudication of computed tomographic indices of adiposity and muscle quantity (Granados et al, 2019;Oh et al, 2022), fitness (Shah et al, 2022), cardiac phenotypes (Shah et al, 2016), and neurocognitive assessments (Reis et al, 2013) have been previously described.…”