Ten-year clinical outcomes for patients undergoing lower extremity endovascular interventions

Katsuki, Tomonori; Yamaji, Kyohei; Hiramori, Seiichi; Tomoi, Yusuke; Soga, Yoshimitsu; Ando, Kenji

doi:10.1016/j.jvs.2020.02.026

Cited by 6 publications

(5 citation statements)

References 38 publications

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“…A validation cohort data set employed the data of IC patients in the FP group. 10 Two-sided p < 0.05 was considered to be statistically significant. All the analyses were performed using JMP statistical software (version 14.2.0; SAS Institute, Cary, NC, USA).…”

Section: Discussionmentioning

confidence: 99%

“…Using an external validation cohort, the performance of the developed model was examined by the Kaplan–Meier curves to assess for discrimination. A validation cohort data set employed the data of IC patients in the FP group 10 . Two‐sided p < 0.05 was considered to be statistically significant.…”

Section: Methodsmentioning

confidence: 99%

“…[6][7][8][9] However, the clinical impact of newly developed lesions could not be disqualified in patients who underwent EVT. 10 Thus, we sought to evaluate the clinical outcomes including both target lesions and newly developed lesions related events in PAD patients after their first EVT by using multicenter data.…”

Section: Introductionmentioning

confidence: 99%

“…After the introduction of new devices for FP lesion such as drug‐eluting stents, drug‐coated balloons and heparin‐bonded covered stents, the risk of undergoing target lesion revascularization (TLR) substantially decreased 6‐9 . However, the clinical impact of newly developed lesions could not be disqualified in patients who underwent EVT 10 …”

Section: Introductionmentioning

confidence: 99%

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New lesion after endovascular therapy of femoropopliteal lesions for intermittent claudication

Katsuki

Yamaji

Soga

et al. 2021

Cathet Cardio Intervent

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Background: Although the incidence of target lesion revascularization (TLR) was decreased in patients who underwent endovascular therapy (EVT) for femoropopliteal (FP) lesions, the clinical impact of newly developed lesions could not be disqualified in those patients.Methods: Between January 2012 and December 2018, 911 patients with intermittent claudication (IC) who have not been previously treated for this condition underwent a successful EVT for de novo FP lesions in a multicenter registry (WATERMELON registry: neW lesion AfTer EndovasculaR therapy for interMittEnt cLaudicatiON).Results: The mean follow-up duration was 3.5 ± 1.9 years. At 5 years, 53% patients underwent limb revascularization, (new lesion: 42% and TLR: 31%). We developed an ordinal risk score to predict the possibility of new lesion revascularization the following risk factors: body mass index (<23 kg/m 2 , 1 point), diabetes (2 points), hemodialysis (3 points), and atrial fibrillation (2 points). The patients were divided into three groups: low risk group (0-1 points: N = 283), intermediate risk group (2-3 points: N = 395), and high risk group (≥4 points: N = 233). The cumulative 5-year incidence of new lesion revascularization was 28% in the low risk group, 40% in the intermediate group, and 68% in the high risk group (p < 0.001).Conclusion: within 5 years after the first EVT, more than half of the patients underwent limb revascularization. Of these patients, 42% underwent new lesion revascularization. Patients with a body mass index <23 kg/m 2 , diabetes, hemodialysis, and atrial fibrillation had increased risk for new lesion revascularization.

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Section: Discussionmentioning

confidence: 99%

Section: Methodsmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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New lesion after endovascular therapy of femoropopliteal lesions for intermittent claudication

Katsuki

Yamaji

Soga

et al. 2021

Cathet Cardio Intervent

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“…4,5 The femoropopliteal artery is the most frequent location within PAD requiring EVT, which sometimes demands complex procedures for lesions, including total occlusion. 6,7 Indeed, approximately 30% to 50% of femoropopliteal artery lesions showed total occlusion in a real-world EVT registry. [8][9][10] In contrast, the prevalence of total occlusion in chronic coronary syndrome (CCS) from percutaneous coronary intervention (PCI) registry was reported to be 3% to 5%, and showed a considerable difference between PAD and CAD.…”

Section: Introductionmentioning

confidence: 99%

Angioscopic Findings of Stenosis Versus Occlusion in Femoropopliteal Artery Disease

et al. 2022

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Background: Despite the increase in the number of patients with peripheral artery disease (PAD), the pathophysiology is not fully elucidated. Recently, angioscopy with a 0.48-megapixel equivalent resolution camera became available for patients with PAD. We aimed to compare the plaque component between native stenosis and occlusion in the femoropopliteal artery using this modality. Materials and Methods: Thirty-two consecutive patients who underwent endovascular treatment for native femoropopliteal artery disease with angioscopy were studied. The major angioscopic classifications of each lesion were defined as follows: atheromatous plaque (AP) was defined as luminal narrowing without any protrusion, calcified nodule (CN) was defined as a protruding bump with surface irregularity, a mainly reddish thrombus was defined as organizing thrombus (OG), and organized thrombus (OD) was defined by more than half of the thrombus showing a whitish intima-like appearance. Results: A total of 34 lesions (stenosis, n=18; occlusion, n=16) from 32 patients were included. All stenotic lesions showed AP or CN (n=8 [44%], n=10 [56%], respectively), whereas all occluded lesions showed OG or OD (n=5 [31%], n=11 [69%], respectively), which amounted to a statistically significant difference (p<0.001). In occluded lesions, stiff wires (>3 g) were required to cross all lesions classified as OD, whereas this was not always necessary for lesions classified as OG (11 [100%] of 11, 1 [25%] of 5, respectively; p=0.04). Yellow color plaques were observed to a similar degree in all angioscopic classifications. Major adverse limb events, defined as amputation and any reintervention at 12 months, were highly variable, depending on the angioscopic findings, and tended to be more frequently observed in CN and OD (13% in AP, 40% in CN, 0% in OT, and 36% in OD, p=0.25). Conclusion: Angioscopy revealed varying components in stenosis and occlusion with different degrees of clinical impact. This may provide new information on the pathophysiology of PAD.

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Long-Term Outcomes of Anatomical and Extra-Anatomical Bypass for the Treatment of Unilateral Iliac Artery Lesions a Systematic Review Aggregated Data and Individual Participant Data Meta-Analysis

Bontinis,

Koudounas

et al. 2024

Annals of Vascular Surgery

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Ten-year clinical outcomes for patients undergoing lower extremity endovascular interventions

Cited by 6 publications

References 38 publications

New lesion after endovascular therapy of femoropopliteal lesions for intermittent claudication

New lesion after endovascular therapy of femoropopliteal lesions for intermittent claudication

Angioscopic Findings of Stenosis Versus Occlusion in Femoropopliteal Artery Disease

Long-Term Outcomes of Anatomical and Extra-Anatomical Bypass for the Treatment of Unilateral Iliac Artery Lesions a Systematic Review Aggregated Data and Individual Participant Data Meta-Analysis

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