Ten year follow up of farmers with farmer's lung.

Cuthbert, O. D.; Gordon, Melissa

doi:10.1136/oem.40.2.173

Cited by 14 publications

(12 citation statements)

References 3 publications

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“…In our study the prevalence of asthma was low before the onset of farmer's lung and there was an increased incidence of asthma during the first years after an episode of farmer's lung. This finding confirms previous findings with smaller groups of patients (3)(4)(5).…”

Section: Discussionsupporting

confidence: 83%

“…In our previous study of 101 farmer's lung patients, the prevalence of asthma was also 7% at the 5-year follow-up (3). In a 10-year follow-up study of (5).…”

Section: Discussionmentioning

confidence: 99%

“…However, some farmer's lung patients may also show an obstructive pattern in inhalation challenge with moldy hay or other offending antigens (1,2). In a few studies asthma has also been reported in 7% to 18% of patients during follow-up after an episode of farmer's lung (3)(4)(5).…”

mentioning

confidence: 99%

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Asthma in patients with farmer's lung during a five-year follow-up

Kokkarinen

H²,

Terho³

1997

Scand J Work Environ Health

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Objectives This study assessed the incidence of asthma in patients with farmer's lung. Methods The study population consisted of 103 1 patients who had occupational fanner's lung diagnosed from 1983 to 1988. The cases of farmer's lung were registered in the nationwide Register of Occupational Diseases by the Finnish Institute of Occupational Health, and all the patients in the study had received compensation from the insurance company for an occupational disease. The diagnosis of asthma was based on entitlement to a special refund for asthma medication costs from the national sickness insurance program. Results Seventy-four cases of asthma were found among farmers with farmer's lung up to the end of the 5 years following the year of the diagnosis for farmer's lung. The prevalence of asthma was 1 % in the year preceding the diagnosis. In the year of the diagnosis and during the 5 years of follow-up, asthma was diagnosed in an additional 6% of the patients. C O~C~U S~O~~S The results of this study confirm previous findings of a low prevalence of asthma before the onset of farmer's lung in small groups of patients. However, the results also indicate that the incidence of asthma increases during the first years after an episode of farmers lung. For example, in the present study, asthma was apparent in 7% of the patients 5 years after the diagnosis of farmer's lung.

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Section: Discussionsupporting

confidence: 83%

“…In our previous study of 101 farmer's lung patients, the prevalence of asthma was also 7% at the 5-year follow-up (3). In a 10-year follow-up study of (5).…”

Section: Discussionmentioning

confidence: 99%

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Asthma in patients with farmer's lung during a five-year follow-up

Kokkarinen

H²,

Terho³

1997

Scand J Work Environ Health

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“…Asthma has rarely been reported in patients at the time of the diagnosis of FL [1,3,29,30], but, according to the present study and an earlier study by CUTHBERT and GORDON [31], asthma seems to not be uncommon years after suffering from FL.…”

Section: Discussionmentioning

confidence: 71%

Long-term outcome of pulmonary function in farmer's lung: a 14 year follow-up with matched controls

Erkinjuntti-Pekkanen

Kokkarinen²,

Tukiainen³

et al. 1997

Eur Respir J

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The long-term outcome of pulmonary function was evaluated in farmer's lung (FL) patients compared to representative control farmers. This is, to our knowledge, the first such study which has included a control group. Clinical examinations were conducted in 89 FL patients and 84 control farmers, matched by age, sex, and smoking habits. The mean time after the first diagnosed episode of FL was 14 yrs.The mean transfer factor of the lung for carbon monoxide (TL,CO) was on average 12% lower (p<0.001) in FL patients compared to control farmers. In spirometry, the mean maximum expiratory flow at 50% of vital capacity (MEF50) was lower (p=0.08) in FL patients but there were no differences in mean vital capacity (VC) or forced expiratory volume in one second (FEV1) between FL patients and control farmers. However, airway obstruction, defined as an FEV1/VC less than 88% of predicted, was more common in FL patients than in control farmers (33 versus 17%; p=0.02). Patients who had had recurrent episodes of FL had a significantly lower mean TL,CO compared to those FL patients who had experienced only a single episode.In conclusion, impairment of the pulmonary transfer factor is the most important long-term consequence of farmer's lung. However, farmer's lung may also lead to development of airway obstruction.

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“…Follow-up studies have indicated that the prevalence of asthma [4,9,10,15], airway obstruction or bronchial hyperresponsiveness [1,3,6,11,13] may be increased among patients with farmer's lung. Very few of the studies have included a comparison group that would have allowed for adjustment for the overall risk of asthma among farmers.…”

Section: Introductionmentioning

confidence: 99%