Ten-year outcomes following laparoscopic colorectal resection: results of a randomized controlled trial

Pecorelli, Nicolò; Amodeo, Salvatore; Frasson, Matteo; Vignali, Andrea; Zuliani, Walter; Braga, Marco

doi:10.1007/s00384-016-2587-5

Cited by 10 publications

(8 citation statements)

References 38 publications

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“…When stages are analyzed in patients with colorectal cancer, stage 3 is reported as the most common stage in both laparoscopy and open surgery groups (34.2%, 37.7%, respectively). 15 In our study, our cases were also most frequently stage 3. Although stage 3 was relatively more frequently observed in the conversion group, no statistically significant difference was found among the groups.…”

supporting

confidence: 61%

“…15,34 In our study, the number of removed lymph nodes was similar in all groups and no statistically significant differences were found between the resection methods. The average tumor size in colorectal cancers is 3.5 (1-7) cm in the laparoscopic group and 3.9 (1)(2)(3)(4)(5)(6)(7)(8) in the open surgery group.…”

supporting

confidence: 48%

“…15 In our study, one, two, and three-year survival rates revealed no statistical differences between the resection methods. Nonetheless, there are some limitations in the interpretation of the data in our study.…”

mentioning

confidence: 38%

“…Laparoscopic resection rates in colorectal cancers vary between 27.7% and 51.1%; in our study, laparoscopic resection was performed in 44.8% of the cases. 15,16 Studies show that surgery time is significantly longer in laparoscopic resections (mean 216±53 min) than in open surgery (mean 172±48 min); while the exact length of time cannot be determined in conversion cases. 17 Moreover, as the experience of the surgical team increases, operation time decreases.…”

mentioning

confidence: 99%

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The Effect of Resection Methods on Outcomes in Colorectal Cancers: Does Conversion Matter?

Erdoğdu¹,

Çaycı²

2018

TJCD

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ÖZAmaç: Çalışmamızda kolorektal kanserlerde laparoskopiden açığa konversiyon ve diğer yöntemlerin (laparoskopi ve açık cerrahi) kısa ve uzun dönemde sonuçlarının değerlendirilmesi amaçlanmıştır. Yöntem: Kolorektal kanser nedeniyle aynı merkezde elektif opere edilen 98 hastanın medikal verileri retrospektif olarak değerlendirildi. Hastalar rezeksiyon metoduna göre laparoskopi (n=44), açık (n=43) ve konversiyon (n=11) olarak üç gruba ayrıldı. Gruplarda hastaların demografik özellikler, komorbidite varlığı, tümörün kolonik yerleşimi, kolonoskopide geçiş özellikleri, preoperatif metastaz, rezeksiyon tipi, morbidite ve mortalite, lenf bezi metastazı ve hastalık evresi, takip süreleri, nüks ve genel sağkalım verileri kaydedildi ve karşılaştırıldı. Bulgular: Morbidite en sık konversiyon grubunda (%63,6) olduğu görüldü (p=0,012). Morbidite alt grup analizleri yapıldığında laparoskopi ve open cerrahi grupları arasında istatistiksel farklılık bulunmazken (p=0,752); konversiyon grubunda morbidite görülme oranı hem laparoskopi grubundan hem de open cerrahi grubundan istatistiksel olarak daha yüksek bulundu (sırasıyla p=0,009 ve p=0,025). Takip döneminde nüks laparoskopi grubunda 2 (%4,50) hastada, open cerrahi grubunda 2 (%4,50) hastada görüldü. Konversiyon grubunda hastalık nüksü görülmedi. Bir, iki ve üç yıllık sağkalım açısından gruplar arasında farklılık görülmedi. Sonuç: Kolorektal kanserlerde erken dönemde konversiyon uygulanan hastalarda morbidite daha sık görülmekte; ancak kısa ve uzun dönem onkolojik sonuçlarda rezeksiyon metodları arasında farklılık bulunmamaktadır. Anahtar Kelimeler: Kolorektal kanser, laparoskopi, açık cerrahi, konversiyon Aim: In this study, we aimed to evaluate the short-and long-term outcomes of patients undergoing conversion from laparoscopy to open surgery compared to other methods (laparoscopy and open surgery). Method: The data of 98 patients who underwent elective surgery due to colorectal cancer in a single center were retrospectively analyzed. Based on the resection method, patients were divided into three groups: laparoscopy (n=44), open (n=43), and conversion (n=11). The demographic characteristics, comorbidity, colonic localization, colonic transit properties, preoperative metastasis, resection type, morbidity and mortality, lymph node metastasis, stage, follow-up duration, recurrence, and overall survival data were recorded and compared. Results: The morbidity incidence was highest in the conversion group (63.6%) (p=0.012). There was no statistical difference in the morbidity subgroup analyses between laparoscopy and open surgery groups (p=0.752), whereas the incidence of morbidity in the conversion group was statistically higher than both the laparoscopy and open surgery groups (p=0.009 and p=0.025, respectively). During follow-up, recurrence was observed in two patients (4.50%) in the laparoscopy group and in two patients (4.50%) in the open surgery group. There was no difference in one, two, and three-year survival rates among the three groups. Conclusion: In colorectal cancers,...

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supporting

confidence: 61%

supporting

confidence: 48%

mentioning

confidence: 38%

mentioning

confidence: 99%

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The Effect of Resection Methods on Outcomes in Colorectal Cancers: Does Conversion Matter?

Erdoğdu¹,

Çaycı²

2018

TJCD

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“…No statistically significant difference was reported in the development of anastomotic stricture between the two techniques in a study by Pecorelli et al. [30] detailing the long-term outcome of patients following laparoscopic and conventional operations, and Kellokumpu et al [29] reported similar results to Pecorelli et al in their study comparing laparoscopic and conventional techniques. The rate of development of anastomotic stricture was 18.8% and 6.8% in the present study in patients undergoing laparoscopic and conventional LAR, respectively, and the rate was statistically significantly higher in the laparoscopic LAR group (p=0.014).…”

Section: Discussionmentioning

confidence: 88%

Comparison of Quality of Life Scores in Patients Who Underwent Low Anterior Resection and Abdominoperineal Resection for Tumors of The Rectum

Turan

Yiğit

Türkoğlu

et al. 2019

BJSTR

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Objectives: This study makes a comparison of the quality of life of patients who have undergone different forms of radical surgery for tumors of the rectum. Background: Colorectal carcinoma is the third most common form of cancer among all cancer types, and the most common type of all gastrointestinal system cancers.Methods: Patients who had undergone a Low Anterior Resection (LAR) or an Abdominoperineal Resection (APR) for rectal cancer were compared using the Short Form-36 (SF-36) quality of life measure. Results:The physical function, role limitations due to physical functions, role limitations due to emotional problems, vitality, mental health, social functionality, and general health perception of the patients who underwent APR were statistically and significantly better then in patients who underwent LAR, while no significant difference was found in the bodily pain scores of the two groups. Conclusion:Patients who underwent LAR achieve a quite good quality of life when no complications developed, while their quality of life was poorer than those fitted with a permanent stoma upon the development of complications. In this regard, the APR resection technique may be preferable to restorative procedures when there is a high risk of such complications as anastomotic stricture and anastomotic leakage.

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Laparoscopy may decrease morbidity and length of stay after elective colon cancer resection, especially in frail patients: results from an observational real-life study

et al. 2017

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Ten-year outcomes following laparoscopic colorectal resection: results of a randomized controlled trial

Abstract: In this series, LPS colorectal resection was not associated with a lower long-term morbidity rate when compared to open surgery. Overall, cancer-specific and disease-free survivals were similar in cancer patients who were treated with LPS and open surgeries.

Cited by 10 publications

References 38 publications

The Effect of Resection Methods on Outcomes in Colorectal Cancers: Does Conversion Matter?

The Effect of Resection Methods on Outcomes in Colorectal Cancers: Does Conversion Matter?

Comparison of Quality of Life Scores in Patients Who Underwent Low Anterior Resection and Abdominoperineal Resection for Tumors of The Rectum

Laparoscopy may decrease morbidity and length of stay after elective colon cancer resection, especially in frail patients: results from an observational real-life study

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