Ten‐Year Retrospective Follow‐Up Study of the TiOblast™ Dental Implant

Al‐Nawas, Bilal; Kämmerer, Peer W.; Morbach, Thomas; Ladwein, Catharina; Wegener, Joachim; Wagner, Wilfried

doi:10.1111/j.1708-8208.2009.00237.x

Cited by 63 publications

(62 citation statements)

References 15 publications

(22 reference statements)

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“…This result is slightly higher compared with a recent analysis of Serino and Turri, 22 which assessed signs of peri‐implant disease in 42% of the cases 2 years after a pocket elimination procedure and a bone recontouring treatment. A percentage of 4.46% of implant lost to peri‐implantitis was reported by Al‐Nawas and colleagues 23 in their retrospective study evaluating the cumulative survival rate of a self‐tapping, cylindrical implant system with a conical connection after 10 years of prosthetic loading. The recurrence of suppuration, bleeding, and subsequent bone resorption led to an implant failure in five over 210 (2.38%) implants included in our study.…”

Section: Discussionmentioning

confidence: 85%

10‐Year Follow‐Up of Immediately Loaded Implants with TiUnite Porous Anodized Surface

Degidi

Nardi

Piattelli

2012

Clin Implant Dent Rel Res

125

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Section: Discussionmentioning

confidence: 85%

10‐Year Follow‐Up of Immediately Loaded Implants with TiUnite Porous Anodized Surface

Degidi

Nardi

Piattelli

2012

Clin Implant Dent Rel Res

125

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“…An important aspect in the follow-up study of the dental implants is the possibility to compare data between different studies [50]. Despite of all restrictions, the method of implant-related survival calculation is mostly available in other studies [37,38] and therefore appropriate for comparison among different studies.…”

Section: Discussionmentioning

confidence: 99%

Early outcome of an implant system with a resorbable adhesive calcium–phosphate coating—a prospective clinical study in partially dentate patients

Palarie¹,

Bicer²,

Lehmann³

et al. 2011

Clin Oral Invest

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This study aims to investigate the early outcome of a dental implant with bioactive calcium-phosphate (CaP) coating in the first year of usage in different clinical indications in partially edentulous patients, after early and delayed prosthetic loading. Therefore, in a prospective follow-up study, the cumulative survival and success rate of a conical, self-drilling and self-tapping implant system after 6 months and 1 year post-insertion was evaluated. A total of 311 CaP-coated implants were placed in 124 patients. Seventy-two implants in clinical high-quality bone situation were loaded after 2 weeks post-insertion with the definite restoration; the rest after 6 months. The indication for implant placement was treatment of partial dentate mandible and maxilla. One hundred sixty-three implants were placed in the posterior mandible, 117 in the posterior maxilla. In the frontal maxilla, 25 implants and in the frontal mandible, eight implants were used. In 126 cases (36%), bone augmentation procedures (guided bone regeneration and sinus lift) were performed concomitant with implant placement. The difference between primary and secondary stability (implant stability quotient (ISQ), Periotest, insertion torque), peri-implant clinical parameter as well as survival and success criteria were evaluated. In total, ISQ mean values after 6 months were higher than after implant placement. Periotest values increased in the period of the first 6 months and remained constant afterwards. After 6 months of insertion, the mean bone loss was 0.051 mm. After 12 months, a bone gain with a mean of +0.016 mm was observed; implants in the posterior maxilla showed significant less bone resorption than implants in the posterior mandible (p < 0.0001). In the most of the implants (74%), clinical normal gingival tissue could be observed. In 24%, a mild inflammation was analysed. In 35 implants, a provocation of peri-implant bleeding was possible. In the early loading group, no implant failure was seen. Altogether, one implant in D4 bone has been lost. The cumulative survival rate summed up to 99.7%. In general, implant success assessment analysis according to Albrektsson and Buser displayed success in 99.7% of the implants. With respect to the patient selection including 124 implants with minor and major augmentations as well as early loading prosthetic function, the 1-year clinical use of the studied implant system with CaP coating showed good results, comparable to that of conventional implants without a specific coating. After 1 year, neither special disadvantages nor benefits of CaP-coated implants could be evaluated. Long-term results are further needed.

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“…Furthermore, we observed the expression of the chemokine receptors (CCR1, 2 and 3) on osteoclasts (Figure and 4). As osteoclasts and FBGCs are observed in close proximity during foreign body reactions [Nuss and von Rechenberg, ], it is possible that chemokines produced by FBGCs during peri‐implantitis [Anderson et al, ; Petkovic et al, ; Venza et al, ] work on the receptors expressed by osteoclasts (CCR1, 2 and 3) resulting in increased bone resorption [Oba et al, ; Fransson et al, ; Miyamoto et al, ; Maruotti et al, ] leading to implant loosening [Al‐Nawas et al, ].…”

Section: Discussionmentioning

confidence: 99%

Differential Expression of Chemokines, Chemokine Receptors and Proteinases by Foreign Body Giant Cells (FBGCs) and Osteoclasts

Khan

Hashimi

Khan

et al. 2014

J of Cellular Biochemistry

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Osteoclasts and foreign body giant cells (FBGCs) are both derived from the fusion of macropahges. These cells are seen in close proximity during foreign body reactions, therefore it was assumed that they might interact with each other. The aim was to identify important genes that are expressed by osteoclasts and FBGCs which can be used to understand peri-implantitis and predict the relationship of these cells during foreign body reactions. Bone marrow macrophages (BMM) were treated with receptor activator of nuclear factor kappa B ligand (RANKL) to produce osteoclasts. Quantitative PCR (qPCR) was used to identify the genes that were expressed by osteoclasts and FBGCs compared to macrophage controls. TRAP staining was used to visualise the cells while gelatine zymography and western blots were used for protein expression. Tartrate-resistant acid phosphatase (TRAP), matrix metallo proteinase 9 (MMP9), nuclear factor of activated T cells 1 (NFATc1), cathepsin K (CTSK) and RANK were significantly lower in FBGCs compared to osteoclasts. Inflammation specific chemokines such as monocyte chemotactic protein (MCP1 also called CCL2), macrophage inflammatory protein 1 alpha (MIP1α), MIP1β and MIP1γ, and their receptors CCR1, CCR3 and CCR5, were highly expressed by FBGCs. FBGCs were negative for osteoclast specific markers (RANK, NFATc1, CTSK). FBGCs expressed chemokines such as CCL2, 3, 5 and 9 while osteoclasts expressed the receptors for these chemokines i.e. CCR1, 2 and 3. Our findings show that osteoclast specific genes are not expressed by FBGCs and that FBGCs interact with osteoclasts during foreign body reaction through chemokines.

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Ten‐Year Retrospective Follow‐Up Study of the TiOblast™ Dental Implant

Abstract: With respect to the critical patient selection including a high number of patients with minor and major augmentations, the 10-year clinical use of the studied implant system showed acceptable results.

Cited by 63 publications

References 15 publications

10‐Year Follow‐Up of Immediately Loaded Implants with TiUnite Porous Anodized Surface

10‐Year Follow‐Up of Immediately Loaded Implants with TiUnite Porous Anodized Surface

Early outcome of an implant system with a resorbable adhesive calcium–phosphate coating—a prospective clinical study in partially dentate patients

Differential Expression of Chemokines, Chemokine Receptors and Proteinases by Foreign Body Giant Cells (FBGCs) and Osteoclasts

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