Ten-year risk of cardiovascular events among the adult population of West Tripura District of India by the Framingham risk score: A cross-sectional study

Abstract

Background: Cardiovascular diseases (CVDs) are the leading causes of mortality worldwide. Predicting the 10-year risk of cardiovascular events (CVEs) may save lives through timely intervention. Framingham risk scoring (FRS) can effectively predict this risk. Objectives: This study aimed to estimate the 10-year risk of CVE using FRS and to estimate the prevalence of CVD risk factors and their associations with FRS among adults in the West Tripura District of India. Methodology: This community-based cross-sectional study was conducted from 1 November 2019 to 30 November 2021 in the West Tripura District of India, using FRS 2008 and a pretested interview schedule among 290 individuals aged ≥ 30 years chosen by multistage sampling. Result: The majority, that is 61.7%, of the study subjects had low risk, 18.6% had intermediate risk and 19.7% had high risk of CVE within 10 years. The prevalence of hypertension was 55.6%; diabetes mellitus, 55.9%; smoking, 96.2%; dyslipidaemia, 34.3%; alcohol consumption, 96.2%; physical inactivity, 54%; and obesity, 64.6%. The bivariate analysis detected a significant association of FRS with age, sex, residence, literacy, marital status, obesity, smoking, alcoholism, blood pressure (BP), high-density lipoprotein cholesterol (HDL-C) and glycaemic status of the study subjects. The logistic regression analysis has identified age >50 years, male sex, hypertension, smoking and diabetes mellitus as significant determinants of high FRS. Conclusion: Adults living in the West Tripura District of India have a high prevalence of CVD risk factors. About one-fifth of this population has a high risk of CVE in 10 years. Controlling hypertension, smoking and diabetes mellitus may help reduce this risk.