Ten years survival with excellent outcome after living donor liver transplantation from 70 years old donor for primary hepatic neuroendocrine carcinoma: Case report

Abstract

Living liver donation from elderly donors for the patients with irresectable neuroendocrine liver malignancies can be as safe as deceased donation or liver donation from young donors (age < 50). Living donation from elderly donors might significantly expand the donor pool for patients with liver neuroendocrine tumors (NET) and potentially reduce waiting list mortality. Especially young patients with irresectable NET can benefit from this option. However, case-control studies are needed to verify the advantage of living liver transplantation (LDLT) for the patients with irresectable liver NET and to define selection criteria for these patients.

Clinicopathological Characteristics of the primary and metastatic Hepatic Neuroendocrine Tumors and the relevant Prognosis-Related Factors: A Retrospective Study of 81 Cases in a Single Chinese Center

“…In our study, the majority of the 81 cases were pathologically proven to be the G3 patients (69.14%, 56/81) according to the WHO classification and no differences were found between the 2 groups (P=0.564), which indicated that the NETs of the liver, whatever its primary site is, are highly malignant as previously reported 11 and need a closer monitor and active management. By chance, we also found that WHO histological grading was statistically correlated with differentiation degree in HNETs patients (P=0.032).…”

Clinical analysis of gastroenteropancreatic neuroendocrine tumor with liver metastasis, compared with primary hepatic neuroendocrine tumor

“…In addition, for primary hepatic NET patients with poorer liver functions, liver transplantation is much better than simple excision of the tumor. [13] Rosenau et al [14] reported that the survival rate of 19 cases of hepatic NET patients who received liver transplantation was higher to 87%.…”

Extended Left Hemihapatectomy with Right Hepatic Artery Reconstruction for Primary Hepatic Neuroendocrine Neoplasm: A Brief Report

“…There have been reports in the literature of successful treatment with the ALPPS procedure for 1 case of PHNEN suitable for stage I liver resection [10]. For patients who are not eligible for resection, liver transplantation can also be considered [11,12].…”