Tensile Strength of Absorbable Suture Materials: In Vitro Analysis of the Effects of pH and Bacteria

Chung, Eric; McPherson, Neil; Grant, A. F.

doi:10.1016/j.jsurg.2009.06.007

Cited by 25 publications

(28 citation statements)

References 11 publications

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“…A variety of degradation media used for these degradation studies can be found in the literature, ranging from different simulated body fl uids (SBFs) to sterile urine or bacteria inoculated media. [ 8,44,113,117 ] The impact of different pH values was investigated by means of pH buffered solutions set to values slightly above or below a human physiological pH. [ 113,117 ] Using immersion test setups, the effect of enzymes and bacteria on the degradation behavior of sutures was furthermore investigated by various groups.…”

Section: In Vitro Degradation Studiesmentioning

confidence: 99%

“…[ 8,44,113,117 ] The impact of different pH values was investigated by means of pH buffered solutions set to values slightly above or below a human physiological pH. [ 113,117 ] Using immersion test setups, the effect of enzymes and bacteria on the degradation behavior of sutures was furthermore investigated by various groups. [ 113,118 ] Predominantly, immersion tests are carried out at body temperature (37 °C) in an incubator or an alternative heated device.…”

Section: In Vitro Degradation Studiesmentioning

confidence: 99%

“…[ 113,117 ] Using immersion test setups, the effect of enzymes and bacteria on the degradation behavior of sutures was furthermore investigated by various groups. [ 113,118 ] Predominantly, immersion tests are carried out at body temperature (37 °C) in an incubator or an alternative heated device. [ 44,113,117 ] The use of orbital shakers or magnetic stirrers to obtain fl uid motion within the immersion tests is reported by Tomihata et al [ 116 ] and Stamboulis et al [ 8 ] As a general rule, subsequent to the immersion test, tensile tests are executed to better quantify the effect the degradation environment had on the suture's tensile strength properties.…”

Section: In Vitro Degradation Studiesmentioning

confidence: 99%

“…[ 113,118 ] Predominantly, immersion tests are carried out at body temperature (37 °C) in an incubator or an alternative heated device. [ 44,113,117 ] The use of orbital shakers or magnetic stirrers to obtain fl uid motion within the immersion tests is reported by Tomihata et al [ 116 ] and Stamboulis et al [ 8 ] As a general rule, subsequent to the immersion test, tensile tests are executed to better quantify the effect the degradation environment had on the suture's tensile strength properties. [ 8,113,116,117,119 ] Different in vitro degradation test parameters for polymeric sutures are summarized in Table 5 .…”

Section: In Vitro Degradation Studiesmentioning

confidence: 99%

“…Chung et al [113] Not specifi ed 6 cm 2 mm/s Straight previously incubated in different in vitro degradation media Peak force at breakage REVIEW the detection of early pitting is favorable. The use of degradable metals would furthermore allow a quantifi cation of the degradation state by means of wire diameter measurements.…”

Section: Applied Force and Displacementmentioning

confidence: 99%

See 4 more Smart Citations

Recent Advances in Biodegradable Metals for Medical Sutures: A Critical Review

Seitz

Ďurišin

Goldman

et al. 2015

Adv Healthcare Materials

215

158

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Sutures that biodegrade and dissolve over a period of several weeks are in great demand to stitch wounds and surgical incisions. These new materials are receiving increased acceptance across surgical procedures whenever permanent sutures and long-term care are not needed. Unfortunately, both inflammatory responses and adverse local tissue reactions in the close-to-stitching environment are often reported for biodegradable polymeric sutures currently used by the medical community. While bioabsorbable metals are predominantly investigated and tested for vascular stent or osteosynthesis applications, they also appear to possess adequate bio-compatibility, mechanical properties, and corrosion stability to replace biodegradable polymeric sutures. In this Review, biodegradable alloys made of iron, magnesium, and zinc are critically evaluated as potential materials for the manufacturing of soft and hard tissue sutures. In the case of soft tissue closing and stitching, these metals have to compete against currently available degradable polymers. In the case of hard tissue closing and stitching, biodegradable sternal wires could replace the permanent sutures made of stainless steel or titanium alloys. This Review discusses the specific materials and degradation properties required by all suture materials, summarizes current suture testing protocols and provides a well-grounded direction for the potential future development of biodegradable metal based sutures.

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Section: In Vitro Degradation Studiesmentioning

confidence: 99%

Section: In Vitro Degradation Studiesmentioning

confidence: 99%

Section: In Vitro Degradation Studiesmentioning

confidence: 99%

Section: In Vitro Degradation Studiesmentioning

confidence: 99%

Section: Applied Force and Displacementmentioning

confidence: 99%

See 3 more Smart Citations

Recent Advances in Biodegradable Metals for Medical Sutures: A Critical Review

Seitz

Ďurišin

Goldman

et al. 2015

Adv Healthcare Materials

215

158

View full text Add to dashboard Cite

show abstract

Comparison of Artificial Saliva vs Saline Solution on Rate of Suture Degradation in Oropharyngeal Surgery

Briddell

Riexinger

Graham

et al. 2018

JAMA Otolaryngol Head Neck Surg

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Mechanical properties of commercially available nylon sutures in the United States

Callahan

Lear²,

Kruzic

et al. 2016

J Biomed Mater Res

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Surgeons can choose from a wide selection of commercially available suture brands, which come at a range of prices. There is currently limited evidence in the literature to guide this selection process. This investigation examined the breaking force, stress, and elongation of a variety of commercially available nylon sutures compared to their relative prices. Seven 5-0, nonabsorbable, nylon suture brands were tensile tested in straight, knotted and knot-security configurations according to the procedures outlined by the United States Pharmacopeia for the tensile testing of sutures. Covidien, the cheapest brand tested, had the highest failure load of straight and knot-security tests. Dafilon was found to have the highest breaking force and percent elongation of knot-pull tests. J&J Ethicon and Supramid had the highest percent elongation to failure for straight-pull and knot-security tests, respectively. This study was limited to specific in vitro tensile properties of nylon suture. Other factors affecting suture quality and price, such as needle properties, were not investigated. The data presented in the study provide information for guiding the selection and purchase of sutures according to tensile properties. © 2016 Wiley Periodicals, Inc. J Biomed Mater Res Part B: Appl Biomater, 105B: 815-819, 2017.

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Tensile Strength of Absorbable Suture Materials: In Vitro Analysis of the Effects of pH and Bacteria

Cited by 25 publications

References 11 publications

Recent Advances in Biodegradable Metals for Medical Sutures: A Critical Review

Recent Advances in Biodegradable Metals for Medical Sutures: A Critical Review

Comparison of Artificial Saliva vs Saline Solution on Rate of Suture Degradation in Oropharyngeal Surgery

Mechanical properties of commercially available nylon sutures in the United States

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