Tenth RESTORE Group Meeting: overview

Buckberg, Gerald D.

doi:10.1016/j.ejcts.2006.02.056

Cited by 4 publications

(4 citation statements)

References 17 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Also, the operative techniques in procedures that try to restore septal architecture after RV dysfunction following RV outflow tract (RVOT) obstruction and RV dysplasia [137][138][139] aim to rebuild a normal oblique septal anatomic fiber orientation. It has been reported that RV restoration is a safe, simple, and effective surgical procedure that should be added during PVI in patients with severe RV dilatation and aneurysmal/akinetic RVOT, and it has been stressed the concept that a ''valve-ventricle'' approach rather than the current ''valve only approach'' is needed in dilated RV failure from the vantage point of geometric correction of RV failure [139].…”

Section: Therapeutic Implicationsmentioning

confidence: 99%

Do we have two hearts? New insights in right ventricular function supported by myocardial imaging echocardiography

Vitarelli

Terzano

2009

Heart Fail Rev

View full text Add to dashboard Cite

RV performance is difficult to evaluate, given its geometry, interrelationship with the left ventricle, and sensitivity to alterations in pulmonary pressure. This article focuses on some of the challenges related to the assessment of RV function in the setting of the RV's unique anatomic, physiologic, conventional and newer echocardiographic aspects, and therapeutic implications. The majority of proposed methods of echocardiographic assessment of RV function are based on volumetric approximations of the RV. Such approaches have inherent limitations, first as volume-related measures such as EF are load dependent, second because of the complex geometry of the RV. The issue of RV geometry is usually overcome using geometry-independent parameters such as tricuspid annular excursion and the Tei index. The recent introduction of real-time three-dimensional echocardiography and myocardial imaging echocardiography (tissue Doppler imaging, 1D-strain and 2D-strain echocardiography) implied a great progress in echocardiography. Tissue Doppler imaging allows the quantitative assessment of RV systolic and diastolic function by means of measurement of myocardial velocities. Strain measurements have been shown to correlate well with sonomicrometry segment length measurements both in the inflow and outflow tract of the RV and under different loading conditions. Other findings have been reported in chronic and acute clinical settings. Standard and novel echocardiographic methods of assessment of RV size and performance can help clinicians in the treatment of acute and chronic RV failure and contribute to a better understanding of the peculiar chamber-related functional mechanisms in the context of ventricular interdependent independency.

show abstract

Section: Therapeutic Implicationsmentioning

confidence: 99%

Do we have two hearts? New insights in right ventricular function supported by myocardial imaging echocardiography

Vitarelli

Terzano

2009

Heart Fail Rev

View full text Add to dashboard Cite

show abstract

“…The short-lasting highly localized deformations and the physiologic asynchrony of cardiac deformation can be deciphered accurately only when analyzed in reference to the structural anisotropy of the underlying myocardial architecture. This information became available with the advent of high temporal resolution imaging methods and is fundamental for understanding cardiac physiology, optimization of cardiac therapies and planning of surgical procedures used for restoring the LV geometry (96). Another important objective in attempting to discern the link between the structure and function of a beating heart is to develop accurate computational models that can assimilate all imaging information for planning of proper therapeutic strategies for a given individual patient (97).…”

Section: Final Commentsmentioning

confidence: 99%

Left Ventricular Structure and Function

Sengupta

Kořínek

Bělohlávek

et al. 2006

Journal of the American College of Cardiology

433

View full text Add to dashboard Cite

The myofiber geometry of the left ventricle (LV) changes gradually from a right-handed helix in the subendocardium to a left-handed helix in the subepicardium. In this review, we associate the LV myofiber architecture with emerging concepts of the electromechanical sequence in a beating heart. We discuss: 1) the morphogenesis and anatomical arrangement of muscle fibers in the adult LV; 2) the sequence of depolarization and repolarization; 3) the physiological inhomogeneity of transmural myocardial mechanics and the apex-to-base sequence of longitudinal and circumferential deformation; 4) the sequence of LV rotation; and 5) the link between LV deformation and the intracavitary flow direction observed during each phase of the cardiac cycle. Integrating the LV structure with electrical activation and motion sequences observed in vivo provides an understanding about the spatiotemporal sequence of regional myocardial performance that is essential for noninvasive cardiac imaging.

show abstract

“…The septum is composed of oblique fibers surrounded externally by the right segment of the basal loop that contains predominantly transverse fibers in the intact heart. This obliquity of septal fiber orientation determines left and right sides of septum which contributes to LV systolic and diastolic function [35,36]. The septum also comprises of two muscle layers which works as a single unit contributing to biventricular geometry and function [37].…”

Section: Discussionmentioning

confidence: 99%

The Prevalence of Left Ventricular Hypertrophy and Altered Geometry in Patients with Right Ventricular Diastolic Dysfunction

Brindisi¹,

Sharma²,

Matteo³

2011

J Clinic Experiment Cardiol

View full text Add to dashboard Cite

Background: Left ventricular diastolic dysfunction (LVDD) associated with left ventricular hypertrophy (LVH) has been reported to play a major role in cardiovascular heart failure. Although, right ventricular diastolic dysfunction (RVDD) in patients with LVH was known to be clinically relevant, no systematic study had been performed regarding this relationship between left ventricular (LV) geometry associated with LVH and RVDD. The goal of this study was to evaluate an association between RVDD; LVDD, LVH and LV altered geometry for early diagnosis of heart failure. Methods and Results:Out of 426 patients, 396 patients (93%) were found to have both RVDD and LVDD. In this cohort, LV concentric geometry (LVCG) was identified in 138 patients (32.3%). RVDD and LVDD were diagnosed by measurement of E/A and tissue doppler imaging (E'/A') for mitral and tricuspid valves. The mean value of mitral E/A in the LVCG group was lower than that of controls; 0.63±0.03 vs. 1.44±0.03, p<0.02. Mitral E'/A' was also lower in LVCG than that of controls; 0.60±0.02 vs. 1.36±0.03, p<0.01. Similarly, E/A of Tricuspid valve in patients with LVCG was found to be lower than E/A of Tricuspid valve of controls; 0.52±0.07 vs. 0.69±0.02, p<0.001 and E'/A' of tricuspid valve was lower than that of controls; 0.44±0.02 vs. 0.63±0.06, p<0.05. Conclusions:This study demonstrated that simple doppler trans-valvular inflow parameters and tissue doppler imaging may identify patients with biventricular diastolic dysfunction. This finding was more often observed in patients with LV concentric geometry, a pattern associated with an increased risk of cardiovascular events.

show abstract

Tenth RESTORE Group Meeting: overview

Cited by 4 publications

References 17 publications

Do we have two hearts? New insights in right ventricular function supported by myocardial imaging echocardiography

Do we have two hearts? New insights in right ventricular function supported by myocardial imaging echocardiography

Left Ventricular Structure and Function

The Prevalence of Left Ventricular Hypertrophy and Altered Geometry in Patients with Right Ventricular Diastolic Dysfunction

Contact Info

Product

Resources

About