Terahertz spectroscopic detection of amino acid molecules under magnetic field

Meng, Qinghao; Wang, Guoyang; Huang, Haiyun; Yang, Yizhou; Su, Bo; Zhang, Cunlin

doi:10.1016/j.heliyon.2022.e11414

Cited by 1 publication

(1 citation statement)

References 13 publications

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“…[42][43][44][45] However, for biological solutions, the large amount of moisture in the solution leads to the strong absorption of terahertz waves, making direct detection of biological solutions via transmission THz-TDS systems ineffective. [46,47] To address this, there is an urgent need to develop a terahertz sensor that is extremely sensitive to minute changes in hydration state, aiming to balance the absorption of terahertz waves by water and shorten the swelling equilibrium response time, thereby improving detection efficiency of glucose biomolecules. In addition, such continuous, non-invasive detection could ideally be achieved if glucose-sensing hydrogels could be fabricated as flexible, wearable devices, in contrast to today's rigid hydrogel sensors.…”

Section: Introductionmentioning

confidence: 99%

Flexible Specific Determination of Glucose in Solution, Blood Serum, and Sweat Using a Terahertz Hydrogel‐Functionalized Metamaterial

Zhang,

Wang

et al. 2023

Adv Materials Technologies

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Terahertz metamaterials have shown promises in biomolecules detection, however, aqueous solvents such as blood serum strongly absorb the terahertz waves, interfering with the detection. To avoid such interference, an ultrathin, flexible, biogel‐based metamaterial that can specifically detect the transmission of terahertz waves through biomolecules in aqueous solution is proposed and demonstrated. The glucose in water can be detected with a sensitivity of 0.0446 dL mg−1 and a detection limit of 1.64 mg dL−1, as well as glucose in human serum. The metamaterial that detects glucose in human sweat is part of a wearable device. The biosensor functions well for more than 100 detection cycles. The results suggest a strategy for real‐time detection of glucose and potentially other biomolecules.

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