Terapia de resincronización cardiaca y miocardiopatía valvular tras cirugía correctora

Macı́as, Alfonso; Gavira, Juán José; Castaño, Sara; Moreno, José Hernández; Alegría, Eduardo; García‐Bolao, Ignacio

doi:10.1157/13126049

Cited by 2 publications

(1 citation statement)

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“…In an observational, non-comparative study on 40 patients with CRT in the setting of HF after corrective valvular surgery, Macias et al . 14 recently reported an improvement of symptoms, functional capacity and echocardiographic indices, on the basis of a 6 month follow-up.…”

Section: Discussionmentioning

confidence: 99%

Effectiveness of cardiac resynchronization therapy in heart failure patients with valvular heart disease: comparison with patients affected by ischaemic heart disease or dilated cardiomyopathy. The InSync/InSync ICD Italian Registry

Boriani

Gasparini

Landolina

et al. 2009

European Heart Journal

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AimsTo analyse the effectiveness of cardiac resynchronization therapy (CRT) in patients with valvular heart disease (a subset not specifically investigated in randomized controlled trials) in comparison with ischaemic heart disease or dilated cardiomyopathy patients.Methods and resultsPatients enrolled in a national registry were evaluated during a median follow-up of 16 months after CRT implant. Patients with valvular heart disease treated with CRT (n = 108) in comparison with ischaemic heart disease (n = 737) and dilated cardiomyopathy (n = 635) patients presented: (i) a higher prevalence of chronic atrial fibrillation, with atrioventricular node ablation performed in around half of the cases; (ii) a similar clinical and echocardiographic profile at baseline; (iii) a similar improvement of LVEF and a similar reduction in ventricular volumes at 6–12 months; (iv) a favourable clinical response at 12 months with an improvement of the clinical composite score similar to that occurring in patients with dilated cardiomyopathy and more pronounced than that observed in patients with ischaemic heart disease; (v) a long-term outcome, in term of freedom from death or heart transplantation, similar to patients affected by ischaemic heart disease and basically more severe than that of patients affected by dilated cardiomyopathy.ConclusionIn ‘real world’ clinical practice, CRT appears to be effective also in patients with valvular heart disease. However, in this group of patients the outcome after CRT does not precisely overlap any of the two other groups of patients, for which much more data are currently available.

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Section: Discussionmentioning

confidence: 99%