Terbutaline in the Treatment of Status Asthmaticus

Pang, Leila Mei; Rodriguez-Martinez, F.; Davis, William J.; Mellins, Robert B.

doi:10.1378/chest.72.4.469

Cited by 21 publications

(3 citation statements)

References 15 publications

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“…Our study confirms earlier reports suggesting terbutaline to be superior to epinephrine in reversing bronchospasm, with significantly less tachycardia (1, [5][6][7][8][9][10]13). This difference became greater in the older pediatric age groups of 5 and above.…”

Section: Resultssupporting

confidence: 91%

Comparison Between Epinephrine and Terbutaline Injections in the Acute Management of Asthma

1989

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A randomized clinical trial comparing subcutaneous epinephrine and terbutaline injections was conducted in asthmatic children at The Methodist Hospital, Brooklyn, New York. Clinical evaluation using the Asthma Scoring System was done at baseline and serially, every 15 minutes, following injection of either drug. Reversal of wheezing, and changes in respiratory and heart rates were assessed using strict a priori criteria. The patients' differential response to both drugs was assessed by a crossover study when the same patients came subsequently for another episode of wheezing. Our results show terbutaline to be more efficacious at a dose comparable to epinephrine dose.

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Section: Resultssupporting

confidence: 91%

Comparison Between Epinephrine and Terbutaline Injections in the Acute Management of Asthma

1989

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“…Also, terbutaline has been administered by subcutaneous injection in status asthmaticus. 124 Antibiotics are required only if there is clinical or laboratory evidence of bacterial infection. Bacterial pathogens are detected infrequently in acute asthma of childhood.…”

Section: Treatment Of Status Asthmaticusmentioning

confidence: 99%

Asthma in Childhood

Simons¹

2008

Seminars in Respiratory and Critical Care Medicinee

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“…(32) However, terbutalene in the same dose as epinephrine (0.01 ml/kg) has been found to be equally effective. (33) Alternatively Ben Zvi et al found susphrine to be as effective as repeated epinephrine injections. (34) 2.…”

Section: Icu Managementmentioning

confidence: 99%

Intensive Care Management of Status Asthmaticus

Mobley¹

1987

Pediatric Asthma, Allergy & Immunology

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Asthma is a medical emergency that usually can be resolved with prompt appropriate therapy, as was well described in another article in this current edition. However, at times it is necessary to admit the patient for more aggressive therapy. At this time a good history may give clues to those who are at risk for respiratory failure. There are several physical signs and laboratory studies that may give warning to severe asthma or impending respiratory failure. For the patient who progresses into respiratory fail¬ ure, monitoring (invasive and noninvasive) is needed. As an alternative to aminophylline infusion, beta sympathomimetic agonist therapy should be considered. With signs of severe respiratory distress, intubation and mechanical ventilation with controlled peak inspiratory pressures should be employed. Our experience with using extracorporeal membrane oxygénation to treat severe airway obstruction in two infants indicates that this is a new alternative if conventional mechanical ventilation is not effective.

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Terbutaline in the Treatment of Status Asthmaticus

Cited by 21 publications

References 15 publications

Comparison Between Epinephrine and Terbutaline Injections in the Acute Management of Asthma

Comparison Between Epinephrine and Terbutaline Injections in the Acute Management of Asthma

Asthma in Childhood

Intensive Care Management of Status Asthmaticus

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