Terlipressin‐induced foot ischemia

Ata, Fateen; Osman, Ahmed Mohamed Elmudathir Ahmed; Dakhlia, Ines; Zahid, Muhammad

doi:10.1002/ccr3.3570

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2021

2023

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“…The patient showed complete resolution of the rash and healed lesions within a week of follow-up, demonstrating the effectiveness of this approach. Discontinuation of terlipressin has shown complete resolution of necrosis of skin in various previous case reports [ 9 - 12 ].…”

Section: Discussionmentioning

confidence: 83%

Terlipressin-Induced Skin Necrosis While Managing Hepatorenal Syndrome: A Rare Case Report From North India

Sudan¹,

Chaudhary²,

Bethineedi³

et al. 2023

Cureus

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Terlipressin is an analogue of vasopressin and is often used in the treatment of bleeding esophageal varices and also in the treatment of hepatorenal syndrome associated with liver cirrhosis. Although terlipressin is a safe drug, but it has been rarely associated with potentially serious adverse effects like ischemic necrosis of skin involving the abdominal skin, extremities, and scrotal skin. We present one such rare case where terlipressin-induced skin necrosis in bilateral lower extremities in a 48-year-old male while we were managing hepatorenal syndrome in the same.

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Section: Discussionmentioning

confidence: 83%