Terpenoid antifeedants (Part II): The synthesis of drimane and clerodane insect antifeedants

Synthesis of Terpenoid Unsaturated 1,4-Dialdehydes. π-Facial Selectivity in the Diels−Alder Reaction of the 1-Vinyl-2-methylcyclohexene Moiety of Polycyclic Systems with DMAD

“…This strategy has been successfully used to prepare the simplest member of this group of natural products, polygodial ( 1 ), as well as many other drimane sesquiterpenes . In connection with our synthetic studies on scalarane and spongiane terpenoids, we have investigated the potential application of this Diels−Alder reaction to the synthesis of these polycyclic compounds.…”

Botanical Pesticides

“…With the exception of neem, which has been shown to be safe, easily grown or available in large quantities, and is already in use as a pesticide in the developing countries (besides being approved for use on nonfood crops and in nurseries in the United States) (116), other genera and species of these families must meet the following criteria before they can be used commercially: (1) safe for plant and animal life, (2) biodegradable (environmentally safe), (3) ready availability of the plant or capability for cultivation, (4) determination of isolation procedures for the active component or components (or of formulation of extracts prepared from plant parts) or (5) establishment of synthetic procedures for the active components. (117).…”