Terpenoids and Sterols from Hoya multiflora Blume

Ebajo, Virgilio D.; Shen, Chien Chang; Ragasa, Consolacion Y.

doi:10.7324/japs.2015.50406

Cited by 11 publications

(2 citation statements)

References 47 publications

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“…Terpenoids such as αand βamyrin have been reported to have anti-inflammatory effects in rodents, while some authors have also reported their usefulness as painkillers and for treating inflammation (Ebajo et al, 2015;Okoye et al, 2014). These compounds in the seed oil of P. macrophylla suggest their usefulness as a painkiller and an antiinflammatory agent.…”

Section: Resultsmentioning

confidence: 99%

Gas Chromatographic Analysis of Bioactive Compounds in the Seed Oil of Pentaclethra macrophylla (African Oil Bean Tree)

Oyedeji¹,

Azeez²,

Odeyemi³

2021

NRFHH

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This study characterized the bioactive components in the seed oil of Pentaclethra macrophylla to establish its usefulness in replacing costly convectional oils in industrial applications. Identification and quantification of the bioactive attributes were performed using gas-liquid chromatography with flame ionization detector (GC-FID) after extraction with n-Hexane. The main bioactive contents per 100 g in the oil were sitosterol (457.58 mg), campesterol (34.54 mg) and stigma-sterol (18.52 mg) been the most abundant sterols. The oil contained per 100 g β-carotene (15.89 mg), xanthophyll (10.32 mg), lutein (9.22 mg), and neo-xanthin (5.46 mg) as the highest carotenoids. The oil has ɣ- tocopherol (43.83 mg) and α-tocopherol (3.35 mg) also per 100 g. The main terpenes per 100 g in the oil were γ-elemene (17.28 mg), α-caryophyllene (13.06 mg), β-elemene (12.43 mg) and D-limonene (6.11 mg). Terpenoids including β-amyrin, α-amyrin and lupeol were found in trace amounts.

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Section: Resultsmentioning

confidence: 99%

Gas Chromatographic Analysis of Bioactive Compounds in the Seed Oil of Pentaclethra macrophylla (African Oil Bean Tree)

Oyedeji¹,

Azeez²,

Odeyemi³

2021

NRFHH

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“…Baas WJ, Berkel IEM Van, Versluis C, Heerma W, Kreyenbroek MN. 1992 Lupeol (Baas and Figdor 1978;Baas and Niemann 1979;Niemann et al 1979;Ebajo et al 2014;Ebajo, Shen, et al 2015c;Panajon et al 2016;Seeka et al 2017) Lupeol acetate α-amyrin (Baas and Figdor 1978;Niemann et al 1979;Baas et al 1992;Ebajo et al 2015b;Ebajo et al 2015c;Panajon et al 2016) α-amyrin acetate (Ebajo et al 2015c) β-amyrin (Baas and Figdor 1978;Baas and Niemann 1979;Niemann et al 1979;Baas et al 1992;Ebajo et al 2015a;Ebajo et al 2015b;Ebajo et al 2015c;Panajon et al 2016) β-amyrin acetate (Baas and Niemann 1979;Ebajo et al 2015c) β-amyrin cinnamate (Ebajo et al 2015a;Ebajo et al 2015b;Panajon et al 2016)…”

Section: Supplementary Referencesunclassified

Pharmacological properties of Hoya (Apocynaceae): a systematic review

Rumaling,

Fong,

Rao

et al. 2024

Natural Product Research

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In tropical forests, Hoya, a plant with significant indigenous medicinal applications, has been underexplored in pharmacological studies. This systematic review meticulously investigates the diverse pharmacological effects exhibited by various Hoya species on human health. A comprehensive literature search, encompassing Scopus, ScienceDirect, and SpringerLink databases, employed specific keyword combinations ('Hoya' and 'pharmacological properties' OR 'pharmacology property'). The included studies exclusively focused on Hoya's impact on human health. The findings underscore Hoya's potential as a medicinal plant, demonstrating promising attributes such as anticancer, antibacterial, antioxidant, anti-inflammatory, anti-diabetic, antinociceptive, and parasympatholytic effects. Despite these promising indications, the review

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Identification of Bioactive Compounds in Polar and Nonpolar Extracts of Araujia sericifera

Palomino‐Schätzlein

Montaño

Escrig

et al. 2017

PMIO

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Araujia sericifera is a native perennial, climbing laticiferous shrub from South America that is currently naturalized in many other countries. Previous data describe promising properties for A. sericifera, but no systematic study of its bioactive compounds and possible medicinal applications has been conducted to date. In the present study, aerial parts of A. sericifera (leaves, stems, and fruits) were explored by combining GC-MS and NMR spectroscopy analysis for both nonpolar (hexane) and polar (methanol) extracts. The hexanic extracts contained high amounts of pentacyclic triterpenes including two new metabolites, 3-tigloyl germanicol (18) and 3-tigloyl lupeol (19). The methanolic extracts revealed the presence of luteolin-7-glucoside (24), trigonelline (22), and conduritol F (23) as the main constituents. A multivariate study of a meaningful number of extracts allowed us to determine the distribution of compounds inside the plant. A cytotoxic evaluation in vitro showed that both leaf and fruit hexanic extracts presented a moderate activity against human breast carcinoma cell lines (MDA-MB-453 and MCF-7) and human colon carcinoma cell line (HCT-116) by the MTS [3-(4,5-dimethylthiazol-2-yl)-5-(3-carboxymethoxyphenyl)-2-(4-sulfophenyl)-2H-tetrazolium] assay.

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Terpenoids and Sterols from Hoya multiflora Blume

Cited by 11 publications

References 47 publications

Gas Chromatographic Analysis of Bioactive Compounds in the Seed Oil of <i>Pentaclethra macrophylla</i> (African Oil Bean Tree)

Gas Chromatographic Analysis of Bioactive Compounds in the Seed Oil of <i>Pentaclethra macrophylla</i> (African Oil Bean Tree)

Pharmacological properties of Hoya (Apocynaceae): a systematic review

Identification of Bioactive Compounds in Polar and Nonpolar Extracts of Araujia sericifera

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