Terpenoids from Russula lepida and R. amarissima (Basidiomycota, Russulaceae)

Macrocyclic Trichothecenes from Myrothecium roridum Strain M10 with Motility Inhibitory and Zoosporicidal Activities against Phytophthora nicotianae

“…To the best of our knowledge, hamavellones A and B, isolated from a soil fungus, are the only two microbial compounds known that are similar to 14, which we therefore named hamavellone C. 38 Other known cyclopropyl ketones are cyclic sesquiterpenes and are mainly produced by mushrooms. 40,41 The compounds 1−12, 14, and 15 were tested against zoospores of P. nicotianae and a few other microorganisms; results are presented in Tables 3 and 4, respectively. Motility inhibitory and lytic activities against zoospores clearly increased to the maximum applied dose ( Table 3).…”

Roseic Acid and Roseolactones A and B, Furan‐Cucurbitane Triterpenes from Russula aurora and R. minutula (Basidiomycota)

“…Typically, all of these cucurbitane triterpenes had at least one carboxylic acid functionality, and most of them were seco-triterpenes, having the Aring cleaved. These triterpenes have, to date, only been isolated from R. lepida and its close relative R. amarissima, [2][3][4] but in this paper, we demonstrate that similar metabolites also occur in R. aurora Krombh. (syn: R. rosea Quél.)…”

“…Roseic acid 1 bears strong similarities with lepidolide B (4), a cucurbitane triterpenoid isolated from Chinese speci- mens of R. lepida [3] (but not found by us in Italian collections of the same fungus [4] ). Interestingly enough, 4 has a γ-lactone ring instead of a furan one, in the same position.…”

“…[1] Recently, however, a few triterpenes, all belonging to the cucurbitane series, have been isolated from representatives of the genus Russula. Work by Tan et al, [2,3] and by ourselves, [4] has shown the presence of such terpenoids in R. lepida, where they were found together with sesquiterpenes of the aristolane series. Typically, all of these cucurbitane triterpenes had at least one carboxylic acid functionality, and most of them were seco-triterpenes, having the Aring cleaved.…”

Talaflavuterpenoid A, a new nardosinane-type sesquiterpene from Talaromyces flavus

“…On the basis of the above analysis, the structure of 1 was elucidated, named talaflavuterpenoid A. The nardosinane sesquiterpene is an uncommon type of sesquiterpenes in nature, which has been isolated from soft corals [13 -15], plants [16 -18], endophytic fungi [19,20], liverworts [21,22], and gorgonian [23]. This is the first report on the isolation of nardosinane-type sesquiterpene from soil fungus.…”