Test for Catatonia with zolpidem

Catatonia: A Review

“…Zolpidem, a selective γ-aminobutyric acid A agonist with a hypnoselective profile, has been found to be useful in the diagnosis of catatonia (69,70,92). The Zolpidem challenge test is counted as being positive if 10 mg of oral Zolpidem, produces at least 50% reduction in the symptoms of catatonia (70,93) Zolpidem has also been reported to be helpful in the treatment of catatonia in a few case-reports (69)(70)(71).…”

“…The Zolpidem challenge test is counted as being positive if 10 mg of oral Zolpidem, produces at least 50% reduction in the symptoms of catatonia (70,93) Zolpidem has also been reported to be helpful in the treatment of catatonia in a few case-reports (69)(70)(71).…”

Pernicious anemia presenting as catatonia: correlating vitamin B12 levels and catatonic symptoms

“…Mental status examination showed that the patient had general psychomotor slowing, apathy, minimal changes of facial expression, anxiety, a perplexed look, flat affect, poor spontaneous movements, waxy flexibility and facial and manual stereotypies. A catatonia challenge with 10 mg of zolpidem [1] was made at the ED, and after 30 min, the patient recovered from all her symptoms. The presence of 5 catatonic symptoms (immobility/stupor, mutism, staring, waxy flexibility, stereotypies) leads to the diagnosis of catatonia with a great diagnostic power [2].…”

Stratégies diagnostiques et thérapeutiques face aux hallucinations de l’enfant et de l’adolescent

“…À noter que les étiologies de catatonie peuvent être psychiatriques ou organiques [29]. Un test thérapeutique rapide au zolpidem permet généralement de déterminer la participation d'éléments catatoniques à la symptomatologie actuelle qui diminue significativement dans les 45 minutes suivant la prise [30]. …”