Test of a Homeopathic Dilution of Aconitum napellus

Abstract

Background: Although healthy persons often report on reactions to homeopathically diluted substances, the mechanism behind such reactions remains unclear. This study examines whether a distinction can be made between the short-term reactions of healthy volunteers to a homeopathically diluted substance – Aconitum napellus C30 – and to a placebo. Participants and Methods: From the 33 subjects randomized for this double-blind, placebo-controlled crossover study, 27 could be included in the analysis. The study comprised two 7-day-long treatment periods, each including the intake of a study preparation for 3 days and a wash-out period of 4 days. One group was first treated with Aconitum napellus C30 and then with placebo; the other group received the two study preparations in the reverse order. The signs and symptoms before the first treatment and after each treatment were collected, evaluated, weighted and repertorized. Based on this classification the blinded physician assessed these signs and symptoms as study outcome parameter to represent the responses to each of the study preparations. Statistical analysis of the data was performed using the Wilcoxon-Mann-Whitney rank test. Results: Crossover differences yielded statistical significance between the classified reactions towards Aconitum napellus C30 and to placebo (p = 0.004). Conclusions: A clear difference between the reported short-term reactions of healthy subjects towards Aconitum napellus C30 and towards placebo was shown. The crossover design with intra-individual comparisons proved to be adequate to recognize the study preparations and for the statistical analysis of a small population sample.

Investigating Homeopathic Verum and Placebo Globules with UV Spectroscopy

“…In 1 trial, reactions of healthy volunteers towards ac30c globules were assessed in a randomised, double-blind, controlled crossover study, and were significantly different from reactions after placebo intake [17]. In the other trial, the effectiveness of cq6x in patients with restless leg syndrome was examined (L. Rist, personal communication).…”

Circadian aspects of hyperthermia in mice induced by Aconitum napellus

“…Following Mexican homeopathic regulations and starting from the original mother tincture – an ethanolic extract in this case – several dynamizations/succussion (shaking by forceful striking) and serial dilutions in distilled water were performed to obtain 6 th (6C) and 30 th (30C) dilutions. (Note: Acn 30C is a common dosage used in homeopathy[18] and there have been no reported adverse effects from homeopathic remedies above 12C. )[39] The final solutions contained A. napellus , all in decimal dilutions of Hahnemann (dH) in distilled water, were colorless and odorless, and had a 1% alcohol concentration.…”

“…[1617] A double-blind crossover study in 27 healthy volunteers found a difference in reported responses (short-term signs and symptoms) when treated for 3 days with Acn 30 C versus placebo, indicating that Acn at that dose had a recognizable effect. [18]…”

Efficacy Profile of the Homeopathic Combination for Influenza and Acute Respiratory Viral Diseases Treatment and Prevention

“…The effects of homeopathic preparations of aconite were also studied on humans [21,22]. Although healthy people often report a reaction to homeopathic remedies, the mechanism of such reactions remains unclear.…”

“…Although healthy people often report a reaction to homeopathic remedies, the mechanism of such reactions remains unclear. A study was carried out to investigate the differences between short-term effects of the homeopathic preparation Aconitum napellus C30 and placebo on healthy volunteers [22]. Of 33 randomly selected subjects for this doubleblind, placebo-controlled, cross-study, 27 were included in the analysis.…”