"Development of a simulation environment to support intercalibration studies over the Algodones Dunes system," J. Appl. Remote Sens. 12(1), 012008 (2017), doi: 10.1117/1.JRS.12.012008. Abstract. The ability of sensors to detect changes in the Earth's environment is dependent on retrieving radiometrically consistent and calibrated measurements from its surface. Intercalibration provides consistency among satellite instruments and ensures fidelity of scientific information. Intercalibration is especially important for spaceborne satellites without any on-board calibration, as accuracy of instruments is significantly affected by changes that occur postlaunch. To better understand the key parameters that impact the intercalibration process, this paper describes a simulation environment that was developed to support the primary mission of the Algodones Dunes campaign. Specifically, measurements obtained from the campaign were utilized to create a synthetic landscape to assess the feasibility of using the Algodones Dunes system as an intercalibration site for spaceborne instruments. The impact of two key parameters (differing view-angles and temporal offsets between instruments) on the intercalibration process was assessed. Results of these studies indicate that although the accuracy of intercalibration is sensitive to these parameters, proper knowledge of their impact leads to situations that minimize their effect. This paper concludes with a case study that addresses the feasibility of performing intercalibration on the International Space Station's platform to support NASA's CLARREO, the climate absolute radiance and refractivity observatory, mission. © The Authors. Published by SPIE under a Creative Commons Attribution 3.0 Unported License. Distribution or reproduction of this work in whole or in part requires full attribution of the original publication, including its DOI.