Testicular Tumors in Undescended Testes in Children Below 5 y of Age

Mittal, Deepak; Agarwala, Sandeep; Yadav, Deepika; Pramanik, D. D.; Sharma, Mrinal; Bagga, Deepak

doi:10.1007/s12098-014-1667-1

Cited by 7 publications

(13 citation statements)

References 23 publications

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“…Earlier risk of developing testicular tumor in UDT had been considered to be 30-50 times greater than in the general population being highest with IAT intraabdominal testis [8], but recently, it has been estimated as 3-8 times higher than in the general population and most commonly seen in intraabdominal testis [1]. Testicular tumors in UDT usually occur at the same age as testicular tumors in normally descended testes, i.e., 20-40 years [2][3][4]. However, testicular tumors arising in UDT are rare in prepubertal children, particularly in intraabdominal testis [2,3].…”

Section: Discussionmentioning

confidence: 99%

“…Testicular tumors in UDT usually occur at the same age as testicular tumors in normally descended testes, i.e., 20-40 years [2][3][4]. However, testicular tumors arising in UDT are rare in prepubertal children, particularly in intraabdominal testis [2,3].…”

Section: Discussionmentioning

confidence: 99%

“…However, involvement of UDT with tumor in prepubertal children is very rare, particularly in intraabdominal testis [2,3]. Majority of intraabdominal testicular tumors were teratomas with only four cases of yolk sac tumor (YST) in intraabdominal testis reported in the literature [2][3][4][5]. But, no case of intraabdominal/testicular YST with normal preoperative serum alpha-fetoprotein has been reported in the literature to the best of our knowledge.…”

Section: Introductionmentioning

confidence: 98%

“…The incidence of testicular tumors in UDT is 3-8 times greater than in general population with normally descended testes, being most frequently associated with intraabdominal testis [1]. Majority of these testicular tumors in UDT occur in postpubertal cases [2,3]. However, involvement of UDT with tumor in prepubertal children is very rare, particularly in intraabdominal testis [2,3].…”

Section: Introductionmentioning

confidence: 99%

“…Majority of these testicular tumors in UDT occur in postpubertal cases [2,3]. However, involvement of UDT with tumor in prepubertal children is very rare, particularly in intraabdominal testis [2,3]. Majority of intraabdominal testicular tumors were teratomas with only four cases of yolk sac tumor (YST) in intraabdominal testis reported in the literature [2][3][4][5].…”

Section: Introductionmentioning

confidence: 99%

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Yolk sac tumor in intraabdominal undescended testis in a child with normal serum alpha-fetoprotein: a rare case report

et al. 2020

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Background Intraabdominal testicular tumors are rare in prepubertal children, and most of the cases reported are intraabdominal testicular teratoma. The present study reports the first case of intraabdominal testicular yolk sac tumor (YST) with normal preoperative serum alpha-fetoprotein levels and diagnosis confirmed on histopathology and immunohistochemistry. Case Presentation A 2-year-old boy presented with bilateral nonpalpable undescended testes (UDT) and abdominal mass. Preoperative serum alpha-fetoprotein was normal. Contrast-enhanced computed tomography (CECT) scan of whole abdomen revealed a heterogeneous mildly enhancing space-occupying lesion in midline and left side of pelvis, left intraabdominal testis and nonvisualization of right testis. During surgery, the mass was found to involve right testis with one turn of torsion of its pedicle. Derotation of testis was performed, and right radical orchiectomy was performed. Left orchiopexy was also performed at the same time. Histopathology and immunohistochemistry confirmed diagnosis of intraabdominal testicular YST. There was no recurrence or distant metastasis at 12-month follow-up after surgery. Conclusion In a case of nonpalpable UDT and abdominal mass/pain, one should always consider possibility of intraabdominal testicular tumor and should investigate the case with serum tumor markers and ultrasound/CECT abdomen. Further, histology of tumor helps in guiding treatment of condition.

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