Testing an OMERACT MRI Scoring System for Peripheral Psoriatic Arthritis in Cross-sectional and Longitudinal Settings

McQueen, Fiona; Lassere, Marissa; Duer-Jensen, Anne; Wiell, Charlotte; Conaghan, Philip G.; Gandjbakhch, Frédérique; Hermann, Kay-Geert A.; Bird, Paul; Bøyesen, Pernille; Peterfy, Charles; Ejbjerg, Bo; Haavardsholm, Espen A; Coates, Laura C.; Østergaard, Mikkel

doi:10.3899/jrheum.090351

Cited by 34 publications

(26 citation statements)

References 9 publications

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“…The readers had varying degree of MRI experience, but the reliability was overall very good and similar to ICCs from previous OMERACT exercises 36 37. Due to technical difficulties with the anonymisation, we introduced new software prior to the second reading, which may have affected the intrareader reliability.…”

Section: Discussionmentioning

confidence: 52%

Hand osteoarthritis and MRI: development and first validation step of the proposed Oslo Hand Osteoarthritis MRI score

Haugen

Lillegraven

Slatkowsky-Christensen

et al. 2011

Ann Rheum Dis

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Section: Discussionmentioning

confidence: 52%

Hand osteoarthritis and MRI: development and first validation step of the proposed Oslo Hand Osteoarthritis MRI score

Haugen

Lillegraven

Slatkowsky-Christensen

et al. 2011

Ann Rheum Dis

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“…Our own recent study of the MRI features of gout in 47 patients showed bone marrow edema to be present in 36% of those with uncomplicated gout (when it was often mild) but to be almost universal in those with gout complicated by osteomyelitis (when it was usually florid) [19]. In RA, MRI bone marrow edema is related to inflammatory osteitis [5,6]; in osteoarthritis, it is thought to indicate fibrosis and necrosis within subcortical bone [7]. In gout, the pathological correlate of MRI bone marrow edema remains unknown, and further studies are required to elucidate this.…”

Section: Joint Pathology In Goutmentioning

confidence: 99%

“…Scoring systems have been developed to quantify joint inflammation and destruction by using imaging and these are now in routine use in clinical trials to provide sensitive measures of drug efficacy in rheumatoid arthritis (RA) and psoriatic arthritis (PsA) [4,5]. In gout, the applications of advanced imaging are only now starting to be explored and are of particular relevance to the clinician assessing the impact of urate-lowering therapies [6].…”

Section: Introductionmentioning

confidence: 99%

Imaging in gout - What can we learn from MRI, CT, DECT and US?

2011

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There are many exciting new applications for advanced imaging in gout. These modalities employ multiplanar imaging and allow computerized three-dimensional rendering of bone and joints (including tophi) and have the advantage of electronic data storage for later retrieval. High-resolution computed tomography has been particularly helpful in exploring the pathology of gout by investigating the relationship between bone erosions and tophi. Magnetic resonance imaging and ultrasonography can image the inflammatory nature of gouty arthropathy, revealing synovial and soft tissue inflammation, and can provide information about the composition and vascularity of tophi. Dual-energy computerized tomography is a new modality that is able to identify tophi by their chemical composition and reveal even small occult tophaceous deposits. All modalities are being investigated for their potential roles in diagnosis and could have important clinical applications in the patient for whom aspiration of monosodium urate crystals from the joint is not possible. Imaging can also provide outcome measures, such as change in tophus volume, for monitoring the response to urate-lowering therapy and this is an important application in the clinical trial setting.

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“…Numerous reports emphasize the dominant role of MRI in the diagnosis of arthritis, particularly in the evaluation of synovial inflammation, effusion and erosions [38,39]. However, the role of ultrasound is always noticeable.…”

Section: Discussionmentioning

confidence: 99%

The comparison of efficacy of different imaging techniques (conventional radiography, ultrasonography, magnetic resonance) in assessment of wrist joints and metacarpophalangeal joints in patients with psoriatic arthritis

Walecki

2013

Pol J Radiol

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SummaryBackground:Psoriatic arthritis (PsA) is a chronic inflammatory joint disease which develops in patients with psoriasis. The rheumatoid factor is characteristically absent in the serum of PsA patients. Etiology of the disease is still unclear but a number of genetic associations have been identified. Inheritance of the disease is multilevel and the role of environmental factors is emphasized. Immunology of PsA is also quite complex. Inflammation is caused by immunological reactions leading to a release of kinins. Destructive changes in bones usually appear after a few months from the onset of clinical symptoms.Material/Methods:PsA typically involves joints of the axial skeleton with an asymmetrical patern. The spectrum of symptoms includes inflammatory changes in attachments of articular capsules, tendons, and ligaments to bone surface. The disease can have a diverse clinical course but usually manifests as oligoarthritis.Results:Imaging plays an important role in the diagnosis of PsA. Classical radiography has been used for this purpose for over a hundred years. It allows to identify late stages of the disease, when bone tissue is affected. In the last 20 years however many new imaging modalities, such as ultrasonography (US), computed tomography (CT) and magnetic resonance (MR), have been developed and became important diagnostic tools for evaluating rheumatoid diseases. They enable the assessment and monitoring of early inflammatory changes.Conclusions:As a result, patients have earlier access to modern treatment and thus formation of destructive changes in joints can be markedly delayed or even avoided.

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Testing an OMERACT MRI Scoring System for Peripheral Psoriatic Arthritis in Cross-sectional and Longitudinal Settings

Abstract: Further development and testing of the PsAMRIS is planned to improve its performance as a clinical and research tool to identify and measure pathology in peripheral joint PsA.

Cited by 34 publications

References 9 publications

Hand osteoarthritis and MRI: development and first validation step of the proposed Oslo Hand Osteoarthritis MRI score

Hand osteoarthritis and MRI: development and first validation step of the proposed Oslo Hand Osteoarthritis MRI score

Imaging in gout - What can we learn from MRI, CT, DECT and US?

The comparison of efficacy of different imaging techniques (conventional radiography, ultrasonography, magnetic resonance) in assessment of wrist joints and metacarpophalangeal joints in patients with psoriatic arthritis

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