We have selected a sample of 326 young (log t < 8) open star clusters with the proper motions and distances calculated by various authors from Gaia DR2 data. The mean values of their line-of-sight velocities have also been taken from various publications. As a result of our kinematic analysis, we have found the following parameters of the angular velocity of Galactic rotation: Ω 0 = 29.34 ± 0.31 km s −1 kpc −1 , Ω ′ 0 = −4.012 ± 0.074 km s −1 kpc −2 , and Ω ′′ 0 = 0.779 ± 0.062 km s −1 kpc −3 . The circular rotation velocity of the solar neighborhood around the Galactic center is V 0 = 235 ± 5 km s −1 for the adopted Galactocentric distance of the Sun R 0 = 8.0±0.15 kpc. The amplitudes of the tangential and radial velocity perturbations produced by the spiral density wave are f θ = 3.8 ± 1.2 km s −1 and f R = 4.7 ± 1.0 km s −1 , respectively; the perturbation wavelengths are λ θ = 2.3 ± 0.5 kpc and λ R = 2.2 ± 0.5 kpc for the adopted four-armed spiral pattern. The Sun's phase in the spiral density wave is close to χ ⊙ = −120 ± 10 • . 1 e-mail: vbobylev@gaoran.ru et al. 2018; Kounkel et al. 2018) and OSCs (Soubiran et al. 2018; Dias et al. 2018) close to the Sun with unprecedented detail, to detect new OSCs (Beccari et al. 2018), and to study the fine structure of the Hertzsprung-Russell diagram (Babusiaux et al. 2018) important for refining the empirical isochrones and the evolutionary processes, which must result in a deeper understanding of the physics of stars.At relative parallax errors for stars from the Gaia DR2 catalogue less than 10% the radius of the solar neighborhood with these stars is ∼3 kpc (Fig. 1 in Xu et al. (2018)). This allows one to cover almost the entire Local Arm and to reach the edges of the Perseus and Carina-Sagittarius arms and to determine the parameters of the spiral structure.Previously (Bobylev and Bajkova 2018), based on a sample of ∼500 OB stars with proper motions and parallaxes from the Gaia DR2 catalogue, we refined the Galactic rotation parameters and the parameters of the spiral density wave. One might expect that, given the necessary statistics, a kinematic analysis of OSCs using the parameters calculated from Ga-iaDR2 data will allow these results to be confirmed or even improved, because the velocities of OSCs are determined with a higher accuracy than are the velocities of single stars.The goal of this paper is to refine the rotation parameters of the Galaxy and its spiral structure using the latest data on OSCs. For this purpose, we use the mean proper motions and parallaxes of OSCs calculated by various authors exclusively from Gaia DR2 data, while the mean line-of-sight velocities of these OSCs were derived mostly from ground-based observations, although there are cases where they were determined from Gaia DR2 data.