Tethered cord syndrome in a 24-year-old woman presenting with urinary retention

Tareen, Basir; Memo, Mark; Cerone, Jeff; Bologna, Raymond; Flora, R.F.

doi:10.1007/s00192-006-0192-9

Cited by 5 publications

(1 citation statement)

References 11 publications

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“…Therefore, the possibility of TCS should not be overlooked when adult patients present with symptoms such as urinary frequency, urgency, or retention. 46 In addition, other potential urinary symptoms should be investigated, particularly in cases of isolated tight filum terminale or occult tethered cord.…”

Section: Clinical Features Of Tcsmentioning

confidence: 99%

Tethered cord syndrome from pediatric and adult perspectives: a comprehensive systematic review of 6135 cases

He,

Wang,

Liu

et al. 2024

Neurosurgical Focus

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OBJECTIVE This study aimed to investigate the differences in clinical features, diagnostic examination, treatment, and pathological results between adult-onset and pediatric-onset tethered cord syndrome (TCS). METHODS The authors searched the PubMed, Embase, and Cochrane Library databases through January 2023 for reports on TCS, extracting information on clinical features, imaging data, treatment modalities, prognosis, and pathological research results. A total of 6135 cases from 246 articles were included in the analysis. This review was conducted in accordance with the 2020 PRISMA guidelines and registered on PROSPERO. RESULTS The most common adult clinical manifestations were pain, urinary symptoms, and numbness; in children, they were urinary symptoms, skin lesions, bowel symptoms, and unspecific motor deficits. Surgical treatment was the primary approach for both adults and children, with a higher clinical improvement rate observed in adults. However, adults also had a higher rate of surgical complications than children. TCS pathological studies have not yet identified the differences between adults and children, and the pathogenesis of adult-onset TCS requires further investigation. CONCLUSIONS Adult-onset and pediatric-onset TCS exhibit certain differences in clinical characteristics, diagnostic examinations, and treatments. However, significant differences have not been found in current pathological studies between adults and children. Systematic review registration no.: CRD42023479450 (www.crd.york.ac.uk/prospero)

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Section: Clinical Features Of Tcsmentioning

confidence: 99%

Tethered cord syndrome from pediatric and adult perspectives: a comprehensive systematic review of 6135 cases

He,

Wang,

Liu

et al. 2024

Neurosurgical Focus

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Surgery in adult onset tethered cord syndrome (ATCS): review of literature on occasion of an exceptional case

2008

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Tethered cord syndrome, usually discovered in childhood, is a developmental abnormality impairing the longitudinal movement of the spinal cord that can be combined with various forms of spinal dysraphism. Adult onset tethered cord syndrome (ATCS) seems not as rare as once thought, however, low susceptibility in adulthood commonly leads to a delay in diagnosis and therapy. We conducted a meticulous literature research to evaluate the clinical presentation, associated malformations, prognostic factors, as well as the benefits and risks of surgical treatment in ATCS patients. The age of patients at onset of symptoms ranged from 18 to 76 years with a mean of 36.5 years, including 184 males and 202 females. In contrast to the pediatric clientele, pain is the predominant symptom in adults, and elicitating mechanisms like trauma, excessive physical training, or degenerative spinal canal stenosis are reported more often. Surgical untethering aims the restoration of craniocaudal mobility of the spinal cord in order to prevent the further progression of symptoms, to restore neurological function, and to improve pain. In our evaluation of literature, pain was the most responsive symptom after surgical untethering (307 of 368 patients). Sensory and motor symptoms also seem to benefit from the surgery, especially if less than 6 months standing and mild. Improvement could be achieved in 43% (144 of 335 patients) for sensory deficits and 58.6% (191 of 326 patients) for motor deficits. Sphincter troubles are less responsive; they show an improvement in 45.6% (141 of 309 patients). Factors reported to be associated with the postoperative deterioration and/or bad outcome are the split cord malformation, lipomyelomeningocele, previous surgery, rapid motor function worsening experienced shortly before the operation, and long delay in diagnosis. The rate of secondary decline and retethering could not be established in our literature research. We report on an additional case of ATCS with the late onset of symptoms at the age of 49; she underwent surgical untethering with neuronavigational guidance. Performing neuronavigational guidance on the basis of multimodal images (computed tomography and magnetic resonance imaging fused with the intraoperative biplanar X-ray) in our patient showed substantial benefit in the surgical orientation within a complex skeletal and neuronal anomaly.

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Insuficiencia renal como debut de un síndrome de médula anclada en el adulto

Caballero

2011

Neurología

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Tethered cord syndrome in a 24-year-old woman presenting with urinary retention

Cited by 5 publications

References 11 publications

Tethered cord syndrome from pediatric and adult perspectives: a comprehensive systematic review of 6135 cases

Tethered cord syndrome from pediatric and adult perspectives: a comprehensive systematic review of 6135 cases

Surgery in adult onset tethered cord syndrome (ATCS): review of literature on occasion of an exceptional case

Insuficiencia renal como debut de un síndrome de médula anclada en el adulto

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