Tetracera scandens as a Medicinal Plant: Secretory Structures, Histochemistry, and Antibacterial Activity

Muliyah, Evi; Sulistijorini, Sulistijorini; Sulistyaningsih, Yohana Cecilia; Rafi, Mohamad

doi:10.11594/jtls.08.01.12

Cited by 10 publications

(9 citation statements)

References 21 publications

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“…Tetracera scandens is a Southeast Asian medicinal plant with several indications, including diabetes mellitus, hepatitis, rheumatism, urinary illnesses, hypertension and diarrhea [16]. Muliyah et al have demonstrated the antibacterial potential of the methanol extract of T. scandens stem as a proposed mechanism of the antidiarrheal activity of the plant [17]. Moreover, an in vivo study has been conducted to investigate the hepatoprotective and the antioxidant potential of the ethanol extract of T. scandens leaves.…”

Section: Introductionmentioning

confidence: 99%

Investigation of α-Glucosidase Inhibitory Metabolites from Tetracera scandens Leaves by GC–MS Metabolite Profiling and Docking Studies

et al. 2020

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Stone leaf (Tetracera scandens) is a Southeast Asian medicinal plant that has been traditionally used for the management of diabetes mellitus. The underlying mechanisms of the antidiabetic activity have not been fully explored yet. Hence, this study aimed to evaluate the α-glucosidase inhibitory potential of the hydromethanolic extracts of T. scandens leaves and to characterize the metabolites responsible for such activity through gas chromatography–mass spectrometry (GC–MS) metabolomics. Crude hydromethanolic extracts of different strengths were prepared and in vitro assayed for α-glucosidase inhibition. GC–MS analysis was further carried out and the mass spectral data were correlated to the corresponding α-glucosidase inhibitory IC50 values via an orthogonal partial least squares (OPLS) model. The 100%, 80%, 60% and 40% methanol extracts displayed potent α-glucosidase inhibitory potentials. Moreover, the established model identified 16 metabolites to be responsible for the α-glucosidase inhibitory activity of T. scandens. The putative α-glucosidase inhibitory metabolites showed moderate to high affinities (binding energies of −5.9 to −9.8 kcal/mol) upon docking into the active site of Saccharomyces cerevisiae isomaltase. To sum up, an OPLS model was developed as a rapid method to characterize the α-glucosidase inhibitory metabolites existing in the hydromethanolic extracts of T. scandens leaves based on GC–MS metabolite profiling.

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Section: Introductionmentioning

confidence: 99%

Investigation of α-Glucosidase Inhibitory Metabolites from Tetracera scandens Leaves by GC–MS Metabolite Profiling and Docking Studies

et al. 2020

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“…A woody climber, Tetracera scandens was in full bloom when we found it at the roadside of the main road to the Lasitae PF (Figure 11a). This plant grows widely in India, China, Indonesia, Myanmar, Philippines, Thailand, Malaysia, and Vietnam (Thanh et al, 2015;Muliyah et al, 2017). The trunk can be used as a source of drinkable water if it is unavailable in the forest.…”

Section: Discussionmentioning

confidence: 99%

The Flora Diversity of Lasitae Protected Nature Forest and the Nearby Area, District of Barru, South Sulawesi

Sari

Astuti

Susandarini

et al. 2020

J.Tropical Biodiversity Biotechnology

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An expedition to Lasitae Protected Forest in District of Barru, South Sulawesi was undertaken to collect living plants for Pucak Botanic Garden, South Sulawesi. The aims were to investigate the diversity of the plants and as a dedication to the Expedition of the Republic of Indonesia Corridor Sulawesi. Using an explorative method, we collected the plants and recorded all data in the field following the tracks assisted by the field guide. A total of 179 collection-numbers have been collected from this dry lowland forest including the data for the local names. Many potential and valuable plants occur in the forest, 13 plants were highlighted in this paper for its conservation status, the potentiality for various purposes or its uniqueness: Diospyros celebica Bakh. or streak ebony (Ebenaceae), Arenga pinnata (Wurmb.) Merr. (Arecaceae), Phyllanthus lamprophyllus Mull.Arg. (Phyllanthaceae), Cycas rumphii Miq. (Cycadaceae), Lagerstroemia speciosa (L.) Pers. (Lythraceae), Garcinia celebica L. (Clusiaceae), Nervilia aragoana Gaud. (Orchidaceae), Phalaenopsis amabilis (L.) Blume (Orchidaceae), Ophioglossum reticulatum L. (Ophioglossaceae), Tetracera scandens (L.) Merr. (Dilleniaceae), Derris trifoliata Lour., Phytocrene bracteata Wall. (Icacinaceae), and Dioscorea hispida Dennst. Buchanania arborescens (Blume) Blume and Ardisia elliptica Thunb. can easily be found and widely spread.

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“…Some neighboring cells were smaller, some bigger and some nearly the same sized. According to Muliyah et al (2018), idioblast can be distinguished by the cell content since idioblast is morphologically similar to neighboring cells. In the present study, idioblast stained red color more intense than neighboring cells, possibly indicating the cell content.…”

Section: Microscopic Evaluation Of Leafmentioning

confidence: 99%

Essential oils from Vitex trifolia as an effective repellent for Aedes aegypti

2020

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Abstract. Arpiwi NL, Muksin IK, Kriswiyanti E. 2020. Essential oils from Vitex trifolia as an effective repellent for Aedes aegypti. Biodiversitas 21: 4536-4544. Vitex trifolia is a shrub or small tree grown wild from family Verbenaceae commonly found in the sandy shore habitat of the tropicals and sub-tropical countries. This research aims to measure the essential oils yield of V. trifolia leaves, to investigate the secretory cells of the leaf, and to measure repellent activity of the essential oils against Aedes aegypti. Leaves and soil samples were taken from Panjer, Sanur, and Sidakarya Villages of Denpasar, Bali Indonesia. Oil was extracted from fresh leaf samples using steam distillation. The essential oils were analyzed for its constituents using Gas Chromatography-Mass Spectrometry. The leaf cross-sections were prepared using paraffin embedding method and stained with safranin. The essential oils of V. trifolia at different concentrations (0, 2, 3, 4, 5, 6% w/w) were formulated into lotions. The yield of essential oils was significantly different from the three locations. The main constituent of the oil was cis-ocimene. The essential oil yield was positively correlated with the sand content. The secretory structures of the leaf were idioblast and glandular trichome. Lotions formulated with the essential oils were soft, not greasy, and not sticky upon application to the skin and non-irritant. Lotions with 5 and 6% essential oils gave 100% protection for 3 hours from Ae. aegypti.

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Tetracera scandens as a Medicinal Plant: Secretory Structures, Histochemistry, and Antibacterial Activity

Cited by 10 publications

References 21 publications

Investigation of α-Glucosidase Inhibitory Metabolites from Tetracera scandens Leaves by GC–MS Metabolite Profiling and Docking Studies

Investigation of α-Glucosidase Inhibitory Metabolites from Tetracera scandens Leaves by GC–MS Metabolite Profiling and Docking Studies

The Flora Diversity of Lasitae Protected Nature Forest and the Nearby Area, District of Barru, South Sulawesi

Essential oils from Vitex trifolia as an effective repellent for Aedes aegypti

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