Tetrakis(2-amino-5-methyl-1,3,4-thiadiazole-N³)chlorocopper(II) chloride monohydrate and tetrakis(2-amino-5-ethyl-1,3,4-thiadiazole-N³)chlorocopper(II) chloride

Abstract

The structures of the title compounds, [CuCl(C(3)H(5)N(3)S)(4)]Cl.H(2)O, (I), and [CuCl(C(4)H(7)N(3)S)(4)]Cl, (II), comprise square-pyramidal Cu centres with four N-bound organic ligands filling the base positions, a Cl atom in the apical position and a Cl(-) as a free counter-ion. The cation and free chloride ion in (II) have fourfold crystallographic symmetry. Hydrogen-bonding associations from the 2-amino H atoms dominate both structures, with the principal acceptors being the chlorides, although in (I), the N4 atoms are also involved. Furthermore, (I) is a hydrate, with the water molecule participating in the hydrogen-bonding network.

Structural, vibrational, thermal and magnetic investigation of novel Co(II), Cu(II), Zn(II) and Hg(II) crystalline metal complexes with 2-amino-5-benzylmercapto-1,3,4-thiadiazole: a low weight model of protonated copolymer resin

“…Each ligand coordinates through the N(1) thiadiazole atom in monomeric units. In these complexes the M(II)-N bond length is about 2 Å , in agreement with other complexes with aromatic ring ligands [19,35,36]. The corresponding distance for the Hg(II) complex is much longer (2.351-2.361 Å ) and similar to the Hg(II)-Cl bond length (2.368-2.383 Å ) (see Table 2) according to the larger ionic radius.…”

“…In the last years the structures and spectroscopic behavior of some crystalline 1,3,4-thiadiazole ligands containing -SO 2 NH 2 (sulfonamido) and -SH (thiol) groups at these positions (particularly position 2) and their metal complexes were determined in our laboratory [7][8][9][10][11][12][13][14][15]. The interactions of metal ions with these ligands have been widely studied [16][17][18][19][20][21][22]. We are interested in analyzing ligand versatility, crystal packing, H-bond strength in the lattice, structural modifications, influence of different substituents at ring positions 2 and 5, coordination sites and vibrational, thermal and magnetic behavior of new crystalline metal complexes of 1,3,4-thiadiazole structurally related ligands.…”

Bis(2-amino-5-methyl-1,3,4-thiadiazole-κN 3)dichloridocobalt(II)

“…For the preparation of the 2-amino-5-methyl-1,3,4thiadiazole ligand, see: Chubb & Nissenbaum (1959). For complexes with this ligand, see: Lynch & Ewington (2001); Neverov et al (1986); Antolini et al (1988).…”

“…wide range of potential applications in the fields of medicine and material science (Katritzky et al, 2010;Seed et al, 2007). The 2-Amino-5-methyl-1,3,4-thiadiazole (amtz) ligand, which contains one S and three N coordination sites is recognized as a potential multidentate ligand to construct some interesting compounds (Lynch et al, 2001;Neverov et al, 1986;Antolini et al, 1988). Herein, the title complex [CoCl 2 (C 3 H 5 N 3 S) 2 ] has been synthesized and characterized structurally.…”

Synthesis and antiproliferative activity of imidazo[2,1- b ][1,3,4]thiadiazole derivatives

“…The starting 2-amino-5-substituted-1,3,4-thiadiazoles were prepared according to the literature, [21][22][23] whereas the various phenacyl bromides are commercially available or prepared by bromination of the corresponding ketones in glacial acetic acid. The 2-aralkyl/alkyl/-6-aryl-imidazo[2,1-b] [1,3,4]thiadiazole derivatives (5-8, 10 and 11) were subjected to electrophilic substitution at position 5 with bromine in the presence of sodium acetate in acetic acid to obtain the 5-bromo derivatives 13-18 in good yield.…”