Tetralogy of Fallot in teenagers and adults: surgical experience and follow-up

Bisoi, Akshay Kumar; Murala, John Santosh Kumar; Airan, Balram; Chowdhury, Ujjwal K.; Kothari, Shyam Sunder; Pal, Hemraj; Patel, Chetan; Cheemalapati, Sai Krishna; Chauhan, Sandeep; Venugopal, Panangipalli

doi:10.1007/s11748-006-0087-1

Cited by 13 publications

(10 citation statements)

References 27 publications

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“…All patients were in NYHA class I. Similar data were reported by Bisoi et al .,11 who stated that total correction of ToF in teenagers and adults offers the best option for long-term, symptom-free survival.…”

Section: Discussionsupporting

confidence: 84%

Late surgical treatment of tetralogy of Fallot

Tchoumi¹,

Ambassa²,

Giamberti³

et al. 2011

CardioVascular Journal of Africa

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AimTo study early post-operative results and follow up of patients over a year old, operated on for tetralogy of Fallot (ToF).MethodsThis retrospective analysis included 22 patients (14 male and eight female) with a mean age of 9.18 ± 6.5 years (range 13.5 months to 26 years), who underwent complete repair of ToF between April 2003 and June 2009. Data from patients’ records, pre-operative cardiac catheterisation studies, operative intervention, and pre-operative and postoperative two-dimensional echocardiographic studies were reviewed. All patients underwent complete repair including closure of ventricular septal defect (VSD). A trans-annular patch was used in 12 patients while an infundibular patch was used in 10 others. Patients were evaluated one, three, six and 12 months after surgery, and annually thereafter. The duration of follow up was from eight months to six years post surgery.ResultsClassical ToF was found in 10 patients. Twelve cases had associated anomalies: two patients with hypoplastic pulmonary artery branches, two with arterial duct malformations, and eight had proximal stenosis of the left branch of the pulmonary artery. NHYA class distribution was as follows: class I: two patients; class II: five subjects; class III: 10 patients; class IV: five subjects. The mean stay in hospital was 15 ± 7 days. Two patients (9%) died during the early post-surgical period. At a mean follow-up interval of 32 ± 9 months, all patients were asymptomatic and in NYHA class I. No late deaths occurred. In three patients, we registered isolated monomorphic ventricular extrasystoles. The right ventricle outflow tract (RVOT) pressure gradient was 29 ± 1.5 mmHg in the acute post-surgical period and it did not change significantly during follow up. The right ventricular function was defined as normal in 95% of the patients in the study and was mildly depressed in 5%.ConclusionEven if treated later in life, our study showed very good surgical results of patients with ToF.

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Section: Discussionsupporting

confidence: 84%

Late surgical treatment of tetralogy of Fallot

Tchoumi¹,

Ambassa²,

Giamberti³

et al. 2011

CardioVascular Journal of Africa

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“…34,40 A total of four studies reported that high scores of quality of life were positively associated with higher achievement in the educational system and higher levels of education in adolescents and young adults with CHD. 28,39,40,43…”

Section: Resultsmentioning

confidence: 99%

Quality of life in adolescents and young adults with CHD is not reduced: a systematic review and meta-analysis

et al. 2015

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“…The reasons are multifactorial -the chronic effects of cyanosis, severe right ventricular dysfunction at presentation, lack of adequate myocardial protection during cardiopulmonary bypass (excessive return due to collateral circulation), and muscle resection on an ''ageing'' right ventricle. 8 Other contributing factors include renal impairment and a bleeding diathesis. In our series, severe right ventricular dysfunction and a failed modified Blalock-Taussig shunt were responsible for the deaths in the tetralogy patients.…”

Section: Mortalitymentioning

confidence: 99%