Tetrasodium EDTA for the prevention of urinary catheter infections and blockages

Moore, Jessica; Kim, Doyoung; Irwin, Nicola; Rimer, Jeffrey D.; McCoy, Colin

doi:10.1039/d2ra06418a

RSC Adv.

2023

DOI: 10.1039/d2ra06418a

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Tetrasodium EDTA for the prevention of urinary catheter infections and blockages

Jessica Moore

Doyoung Kim

Nicola Irwin

et al.

Abstract: Tetrasodium EDTA is an effective chelating agent that prevents struvite crystallisation in P. mirabilis-infected artificial urine, allowing catheters exposed to low tEDTA concentrations to remain unblocked after 168 h.

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2024

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Cited by 2 publications

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Urinary Tract Infection (UTI) Prevention in Patients with Chronic Indwelling Catheters

Cox,

Drerup,

Prickett

2024

Curr Bladder Dysfunct Rep

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Purpose of Review In this review, we discuss urinary tract infections in the setting of indwelling urethral foley catheters. We focus on infection prevention in setting of a chronic indwelling foley and review the recent literature findings on biofilm prevention, catheter duration and exchange intervals, prophylactic supplements, irrigation solutions, and consideration of alternative bladder management options. Recent Findings Ongoing research has found a reduction in UTI rates through the use of biofilm preventing catheters, D-mannose and Methenamine hippurate supplementation, prophylactic antibiotic use at time of catheter exchange, and intravesical antibiotic instillations within the chronically catheterized patient population. Summary Overall, research on recurrent urinary tract infections is fairly robust. However, data focusing on preventing infections in the setting of indwelling catheters is overall lacking. Continued research remains to be done to translate findings to patient care.

show abstract

Urinary Tract Infection (UTI) Prevention in Patients with Chronic Indwelling Catheters

Cox,

Drerup,

Prickett

2024

Curr Bladder Dysfunct Rep

View full text Add to dashboard Cite

show abstract

Plasma activated water pre-treatment substantially enhances phage activity against Proteus mirabilis biofilms

Shambharkar,

Thompson,

McClenaghan

et al. 2024

Biofilm

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Tetrasodium EDTA for the prevention of urinary catheter infections and blockages

Abstract: Tetrasodium EDTA is an effective chelating agent that prevents struvite crystallisation in P. mirabilis-infected artificial urine, allowing catheters exposed to low tEDTA concentrations to remain unblocked after 168 h.

Cited by 2 publications

References 37 publications

Urinary Tract Infection (UTI) Prevention in Patients with Chronic Indwelling Catheters

Urinary Tract Infection (UTI) Prevention in Patients with Chronic Indwelling Catheters

Plasma activated water pre-treatment substantially enhances phage activity against Proteus mirabilis biofilms

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