Textbook Outcomes and Quality of Life Assessment Following Liver Resection for Colorectal Metastasis

Abstract

BackgroundIt is unknown if textbook outcomes (TBOs) correlate with patient‐reported health‐related quality of life (HRQoL) parameters in patients undergoing hepatic resection for colorectal liver metastasises. Understanding this relationship is required to inform treatment decisions and optimise patient care. This single‐centre analysis aims to assess this correlation and provide insight into the impact of liver resection on patient well‐being in this population.MethodsSingle‐centre analysis of all liver resections performed for colorectal liver metastases (CRLM) at our centre from 2018 to 2023. The EuroQol‐5D (EQ‐5D) validated telephone questionnaire was used to assess HRQoL. The impact of a TBO on overall survival and recurrence‐free survival was investigated using Kaplan−Meier curve analysis. A Cox model was used to determine factors associated with improved survival.Results185 patients underwent liver resection for CRLM between 2018 and 2023. 55% of eligible patients completed the EQ‐5D telephone questionnaire. TBOs were achieved in 68.2% of CRLM at our institution. Achieving TBOs in this cohort was associated with improved HRQoL (p = 0.061).ConclusionThis study demonstrates excellent long‐term HRQoL in patients who undergo resection for CRLM. Achieving TBO in this cohort is associated with improved patient‐reported HRQoL. Our findings strengthen the utility of the previously defined textbook outcomes in CRLM.