Textural features based enhanced contrast CT images predicts prognosis to concurrent chemoradiotherapy in stage III esophageal squamous cell cancer

Addition of camrelizumab to docetaxel, cisplatin, and radiation therapy in patients with locally advanced esophageal squamous cell carcinoma: a phase 1b study

“…19 Patients received cervical, thoracic, and upper-abdomen CT scans and upper gastrointestinal radiography at baseline, every 8 weeks during treatment, and every 12 weeks after treatment until disease progression. All patients underwent endoscopic ultrasonography, the standard clinical practice for potential tumor biopsy, at baseline and after 40 Gy radiation 20 (ie, at the end of 4 weeks of radiotherapy) in order to confirm pathological response rates and perform exploration tests. Disease progression in this study was defined as local regional recurrence or distant metastasis.…”

Methodological quality of machine learning-based quantitative imaging analysis studies in esophageal cancer: a systematic review of clinical outcome prediction after concurrent chemoradiotherapy

“…2015–2018 PET/CT Voxel size: 4 × 4 × 5 mm3 dCCRT 152 (train) 32 (val.) HF PyRadiomics (V2.0.1) Clinical and classical PET Xie: 2020 [ 58 ] ESCC 2008–2014 CT 120 kV, 180–280 mA, 3 mm CCRT 57 HF IBEX (V1.0β) Clinical factors Hu: 2020 [ 29 ] ESCC 2007–2018 CT 120 kV, 200–400 mA 2.5 mm (inst 1) 5 mm (inst 2) voxel sizes: 1 × 1 × 5 mm3 nCRT 161 (train) 70 (test) HF PyRadiomics (V3.0) No Luo: 2020 [ 41 ] ESCC 2013–2015 CT 120 kV, 120 mAs, 5 mm dCCRT 160 (train) 66 (val.) HF 3DSlicer (V4.10.2) Clinical factors Li: 2020 [ 54 ] ESCC 2012–2019 CT 120 kV/140 kV, 140–300 mA, 5 mm nCRT 121 HF IBEX Clinical factors Zhang: 2020 [ 47 ] EAD 2010–2016 PET/ CT 120 kVp, 20–200 mA surgery alone, neoadjuvant chemotherapy, and nCRT 190 HF …”

“…The majority of imaging modalities mentioned in the retrieved studies were PET (20/37) [ 28 , 30 , 34 – 40 , 44 – 47 , 49 , 50 , 52 , 55 , 56 , 59 , 61 ], CT (16/37) [ 29 , 31 – 33 , 41 , 43 , 48 , 51 , 53 , 54 , 57 , 58 , 60 , 62 – 64 ], and one cone beam CT (CBCT) [ 42 ]. Although the search criteria included MRI, we did not locate any eligible study in our search.…”

“…More than half of the included studies (19/37) addressed nCRT [ 28 – 30 , 33 , 35 , 38 , 40 , 43 – 47 , 49 , 52 , 54 , 56 , 61 – 64 ]. The majority of patients included in 13 studies were treated specifically with radical CCRT [ 31 , 32 , 36 , 39 , 41 , 42 , 48 , 50 , 51 , 53 , 55 , 58 , 59 ]. In three studies, most patients were treated with CCRT, but the rest received a variety of different treatments depending on their situation [ 34 , 57 , 60 ].…”

“…In this review, classical PET features were defined as intensity-related metrics such as standardized uptake value (SUV), metabolic tumor volume (MTV), and total lesion glycolysis (TLG). There were 8, 7, and 10 studies that combined radiomics with clinical features [ 33 , 41 , 43 , 47 , 51 , 54 , 58 , 60 ], classical PET features [ 39 , 44 , 52 , 55 , 56 , 59 , 61 ], and both clinical and classical PET features [ 30 , 34 – 38 , 40 , 45 , 49 , 50 ], respectively. Among more recently published studies, three included genes as features [ 28 , 63 , 64 ], two included clinical factors with dosimetric features [ 42 , 48 ], one included histopathologic features [ 62 ], and one used a combination of clinicopathological, dosimetric, and hematological features [ 31 ].…”