TGF-β₁ Expression in Kidney Allograft Protocol Biopsies during Cyclosporine: a Therapy

Abstract

In protocol biopsies from patients on low-dose cyclosporine regimen, expression of TGB-β1 was not significantly increased along time since transplantation, and did not correlate with cyclosporine exposure. Our findings suggest that the toxic effects of low-dose cyclosporine on TGF-β expression may be milder than previously thought.