Thai CV risk score and primary prevention in impaired fasting plasma glucose or diabetes mellitus versus normoglycemia in patients with metabolic syndrome

Abstract

Background: Impaired fasting plasma glucose (IFG) as well as diabetes mellitus (DM) may influence the presence of another metabolic syndrome (MetS) components resulting in the different risk of cardiovascular (CV) morbidity and mortality. This study aimed to determine the impact of IFG as well as DM on the 10-year CV risk using Thai CV risk score and primary prevention in complying with CV risk score in these patients. Methods: This cross-sectional study was conducted at the internal medicine clinic, Pathum Thani Hospital, Thailand. The study was approved by the hospital ethics committee and written informed consent was obtained from all patients. Patients having MetS according to the criteria of the International Diabetes Federation were enrolled while those with a history of CVD were excluded. The 10-year CV risk was assessed using the Thai CV risk score. Results: The total of 112 patients were enrolled in the study. They were in old age and female sex was a significantly higher proportion (61.70% vs 35.50%, P = 0.013). Of these, 72.32% had IFG or DM. Proportions of patients with moderate and high CV risk score were significantly greater in IFG/DM group and only 34.48% and 79.31% of patients with moderate or high CV risk score received aspirin and statin. IFG or DM significantly elevated CV risk score (OR = 6.66, 95% CI = 2.29, 19.58). Conclusions: IFG/DM significantly elevated CV risk score in these patients with the strongest impact. The assessment of CV risk is highly recommended for primary prevention and long-term CVD benefit.

Dietary diversity associated with risk of cardiovascular diseases among community-dwelling older people: A national health examination survey from Thailand

“…The Thai CV risk score included sex, age, systolic blood pressure (SBP), the diagnosis of DM, current smoking status and total cholesterol (TC) level, while diastolic blood pressure (DBP), fasting plasma glucose (FPG), Low-density lipoprotein cholesterol (LDL-C), High-density lipoprotein cholesterol (HDL-C), and triglycerides (TG) levels were not included in the score ( 28 ). This score was validated in the Thai population and used as the predictor of the percentage that would develop coronary artery disease, as well as fatal and non-fatal cerebrovascular disease in the next 10 years ( 27 , 29 ). Thus, a higher score meant a higher risk of CVD.…”

Agreement between Thai Cardiovascular Risk Scores and Myocardial Perfusion Imaging: Exploring Associations and Clinical Implications

“…However, it has been observed that the Framingham risk models may overestimate the risk of CVD in the Thai population due to differences in risk profiles and genetic factors. [ 3 ] Therefore, the Thai CV risk score, which is a locally developed tool that considers the unique characteristics of the Thai population, provides a more accurate assessment of CVD risk by utilizing data from a large general practice database and accounting for factors such as diabetes, which is common in Asian populations. [ 4 ]…”