Thalamic tremor

Miwa, Hideto; Hatori, Kozo; Kondo, Tomoyoshi; Imai, Hisamasa; Mizuno, Y

doi:10.1212/wnl.46.1.75

Cited by 100 publications

(54 citation statements)

References 6 publications

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“…nvoluntary abnormal movements (IAMs) caused by strokes are relatively common, [1][2][3][4] and chorea, [3][4][5][6][7][8][9][10][11][12][13][14][15] tremor, [16][17][18][19][20][21][22][23][24][25][26][27][28][29] dystonia, [30][31][32][33][34][35][36][37][38][39][40][41][42][43] parkinsonism, [44][45][46][47][48][49][50]…”

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confidence: 99%

Post-stroke movement disorders: report of 56 patients

Alarcón

2004

Journal of Neurology, Neurosurgery & Psychiatry

258

231

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Background: Although movement disorders that occur following a stroke have long been recognised in short series of patients, their frequency and clinical and imaging features have not been reported in large series of patients with stroke. Methods: We reviewed consecutive patients with involuntary abnormal movements (IAMs) following a stroke who were included in the Eugenio Espejo Hospital Stroke Registry and they were followed up for at least one year after the onset of the IAM. We determined the clinical features, topographical correlations, and pathophysiological implications of the IAMs. Results: Of 1500 patients with stroke 56 developed movement disorders up to one year after the stroke. Patients with chorea were older and the patients with dystonia were younger than the patients with other IAMs. In patients with isolated vascular lesions without IAMs, surface lesions prevailed but patients with deep vascular lesions showed a higher probability of developing abnormal movements. One year after onset of the IAMs, 12 patients (21.4%) completely improved their abnormal movements, 38 patients (67.8%) partially improved, four did not improve (7.1%), and two patients with chorea died. In the nested case-control analysis, the patients with IAMs displayed a higher frequency of deep lesions (63% v 33%; OR 3.38, 95% CI 1.64 to 6.99, p,0.001). Patients with deep haemorrhagic lesions showed a higher probability of developing IAMs (OR 4.8, 95% CI 0.8 to 36.6). Conclusions: Chorea is the commonest movement disorder following stroke and appears in older patients. Involuntary movements tend to persist despite the functional recovery of motor deficit. Deep vascular lesions are more frequent in patients with movement disorders.

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confidence: 99%

Post-stroke movement disorders: report of 56 patients

Alarcón

2004

Journal of Neurology, Neurosurgery & Psychiatry

258

231

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“…It is generally agreed that lesions of these pathways account for the tremor exacerbation during posture and kinetic action. 11,18,32 The resting tremor might have been caused by additional damage to the nigrostriatal pathway, 25,32 which was also involved in the two patients we studied.…”

Section: Discussionmentioning

confidence: 96%

“…7,10,17,18 On the contrary, in individual cases, stereotactic thalamotomy, 15 pallidotomy, 19 and thalamic DBS 16,26 have been reported to alleviate Holmes tremor. Note that following DBS, clinical improvements can occur in associated dystonia and rigidity as well as tremor, as demonstrated in this study and not described previously.…”

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confidence: 99%

Deep brain stimulation of the nucleus ventralis intermedius for Holmes (rubral) tremor and associated dystonia caused by upper brainstem lesions

Nikkhah¹,

Prokop²,

Hellwig³

et al. 2004

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“…A variety of movement disorders (chorea, dystonia and asterixis) might be produced by cerebral infarction [1]; however, isolated, distal postural tremor after thalamic infarction is rarely reported [2, 3, 4]. Mechanism and treatment of this type of tremor remain controversial [4, 5].…”

Section: Introductionmentioning

confidence: 99%

“…Mechanism and treatment of this type of tremor remain controversial [4, 5]. We report a patient who developed such a tremor after thalamic infarction that responded to propanolol and primidone.…”

Section: Introductionmentioning

confidence: 99%