The 1-min sit-to-stand test in cystic fibrosis — Insights into cardiorespiratory responses

Radtke, Thomas; Hebestreit, Helge; Puhan, Milo A.; Kriemler, Susi

doi:10.1016/j.jcf.2017.01.012

Cited by 33 publications

(40 citation statements)

References 29 publications

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“…9 In contrast, continuous S pO 2 measurements during the 1-min STS are hampered by movement artifacts, 13 and our group has re- cently shown that the lowest S pO 2 often occurs during the first minute after the sit-to-stand exercise. 3,13 To our knowledge, no previous study has investigated the prognostic value of oxygen desaturation during the 1-min STS, as previously reported for the 6MWT. 28 In our study, the 1-min STS and the 6MWT showed similar correlations with knee extensor strength.…”

Section: Discussionmentioning

confidence: 73%

“…The subjects were instructed to stand up and sit down as often as possible at a selfchosen speed for 1 min, and the number of sit-to-stand repetitions was counted. Verbal encouragement was not provided during the test, but subjects were informed when 15 s were left until the test terminated at 60 s. 3,4,13,14 Subjects were allowed to stop at any time during the test. A repetition was defined as the legs being completely straight at the end of the stand-up phase, and the bottom had to have clear contact with the chair when sitting down.…”

Section: Measurementsmentioning

confidence: 99%

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The 1-Minute Sit-to-Stand Test in Lung Transplant Candidates: An Alternative to the 6-Minute Walk Test

2019

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BACKGROUND: The 6-min walk test (6MWT) is a well-established functional exercise capacity test in lung transplant candidates. This study aimed to investigate the construct validity of the 1-min sit-to-stand test (1-min STS) as a marker of exercise capacity and knee extensor strength in lung transplantation candidates. METHODS: We retrospectively analyzed data from consecutive subjects referred for lung transplantation evaluation to our institution between 2015 and 2018. RESULTS: 38 subjects were included. We found strong correlations between the normalized 1-min STS and 6MWT (r ‫؍‬ 0.79, P < .001) and moderate correlations between 1-min STS and knee extensor strength (r ‫؍‬ 0.53, P ‫؍‬ .001) and between 6MWT and knee extensor strength (r ‫؍‬ 0.44, P ‫؍‬ .008). The 1-min STS elicited greater dyspnea (P ‫؍‬ .008) and lower oxygen desaturation compared to the 6MWT (P < .001). CONCLUSIONS: The 1-min STS is a valid functional exercise capacity test in lung transplantation candidates. Due to its ease of application, clinical practitioners may consider using the 1-min STS in situations when the 6MWT cannot be performed. Our pilot study may stimulate future research, including a head-to-head comparison between the 6MWT and 1-min STS in a large patient cohort including post-lung transplantation-monitoring.

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Section: Discussionmentioning

confidence: 73%

Section: Measurementsmentioning

confidence: 99%

The 1-Minute Sit-to-Stand Test in Lung Transplant Candidates: An Alternative to the 6-Minute Walk Test

2019

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“…The 1-minute sit-to-stand test (1MSTS) was performed using a standardized protocol [17][18][19] on a conventional chair without armrest and a seat height of 46 cm. For safety reasons, the chair was positioned against a wall.…”

Section: Functional Exercise Capacitymentioning

confidence: 99%

<p>Long-Term Effects of Pedometer-Based Physical Activity Coaching in Severe COPD: A Randomized Controlled Trial</p>

Kohlbrenner

Sievi

Senn

et al. 2020

COPD

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Background and Objective: Limited evidence on long-term effects of physical activity programs in COPD is available. The aim of the study was to investigate the effects of a threemonth program combining physical activity counselling and pedometer-based feedback in addition to usual care, followed by a nine-month unsupervised observation period as compared to usual care in participants with severe to very severe COPD. Methods: Participants were randomized to either a control group receiving usual care or an intervention group receiving motivational support, an activity diary with an individual step count goal (ie, an increase of ≥15% from baseline) and a pedometer in addition to usual care. The intervention ended after three months and an unsupervised observational period followed until twelve months. Primary outcome was daily step count after one year. Results: Seventy-four participants were included, 61 (82%) completed the study. Linear regression modelling, adjusted for baseline step count, showed no significant difference in change in step count after 12 months between the groups (Β = 547.33, 95% CI = −243.55/1338.20). Conclusion: A three-month program combining physical activity counselling and pedometer-based feedback in addition to usual care does not attenuate the declining course of physical activity in participants with severe and very severe COPD during a long term follow-up of one year as compared to usual care. This result was primarily determined by the low intervention response rates to the combined program. Clinical Trial Registration: www.ClinicalTrials.gov, NCT03114241.

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“…32 Dyspnoea scores on 1minSTS did not differ from the 30secSTS but were significantly greater than 5STS (median 2.5 vs 1 vs 0) with a similar pattern of findings for systolic blood pressure (median 30 vs 20 vs 0 mmHg). 32 In comparison to the 6MWT and cardiopulmonary exercise test (CPET), the 1minSTS provoked less oxyhaemoglobin desaturation and a smaller rise in heart rate ( Table 3) 37 Symptom scores for dyspnoea and fatigue were variable, with some studies reporting that they were similar across the tests, 25,39 higher on CPET than 1minSTS, 37 higher on 6MWT than 1 minSTS, 35 or higher on 1minSTS than 6MWT. 16 Exercise prescription: No studies used any of the STS tests for exercise prescription.…”

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confidence: 99%

Home-based or remote exercise testing in chronic respiratory disease, during the COVID-19 pandemic and beyond: A rapid review

et al. 2020

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Objectives: To identify exercise tests that are suitable for home-based or remote administration in people with chronic lung disease. Methods: Rapid review of studies that reported home-based or remote administration of an exercise test in people with chronic lung disease, and studies reporting their clinimetric (measurement) properties. Results: 84 studies were included. Tests used at home were the 6-minute walk test (6MWT, two studies), sit-to-stand tests (STS, five studies), Timed Up and Go (TUG, 4 studies) and step tests (two studies). Exercise tests administered remotely were the 6MWT (two studies) and step test (one study). Compared to centre-based testing the 6MWT distance was similar when performed outdoors but shorter when performed at home (two studies). The STS, TUG and step tests were feasible, reliable (intra-class correlation coefficients >0.80), valid (concurrent and known groups validity) and moderately responsive to pulmonary rehabilitation (medium effect sizes). These tests elicited less desaturation than the 6MWT, and validated methods to prescribe exercise were not reported. Discussion: The STS, step and TUG tests can be performed at home, but do not accurately document desaturation with walking or allow exercise prescription. Patients at risk of desaturation should be prioritised for centre-based exercise testing when this is available.

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The 1-min sit-to-stand test in cystic fibrosis — Insights into cardiorespiratory responses

Abstract: The 1-min STS test elicits a substantial but lower cardiorespiratory response compared to a maximal cycle ergometry CPET. While Power and STS repetitions are both valid outcome measures of functional capacity, STS repetitions are clinically more practical.

Cited by 33 publications

References 29 publications

The 1-Minute Sit-to-Stand Test in Lung Transplant Candidates: An Alternative to the 6-Minute Walk Test

The 1-Minute Sit-to-Stand Test in Lung Transplant Candidates: An Alternative to the 6-Minute Walk Test

<p>Long-Term Effects of Pedometer-Based Physical Activity Coaching in Severe COPD: A Randomized Controlled Trial</p>

Home-based or remote exercise testing in chronic respiratory disease, during the COVID-19 pandemic and beyond: A rapid review

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