The 1998 CDC sexually transmitted diseases treatment guidelines

Abstract

Health care providers who evaluate persons who have or are at risk for sexually transmitted diseases (STDs) should be aware of current national guidelines for STD treatment and should provide assessment and treatment according to these recommendations. The Centers for Disease Control and Prevention STD Treatment Guidelines were developed by using an evidence-based approach incorporating available scientific evidence, specialist knowledge, and consultation with professional organizations and other agencies with diverse perspectives on STD treatment. The guidelines provide recommendations about new antimicrobial agents for the treatment of primary and recurrent genital herpes, a novel patient-applied therapy for genital warts, additional parenteral alternative regimens for the treatment of pelvic inflammatory disease, oral therapy for vaginal candidiasis, and alternative regimens for treatment of chlamydia in pregnancy. Expanded sections in the guidelines also address the management of urethritis, recognition of the acute retroviral syndrome, and the emergence of quinolone-resistant Neisseria gonorrhoeae. Prevention of sexually transmitted hepatitis A and hepatitis B through the use of preexposure vaccinations is discussed.

A Case of Congenital Infection: Missed Opportunities for Prevention and the Importance of Maternal Testing and Screening

“…For example, the Centers for Disease Control and Prevention 2015 Sexually Transmitted Disease guidelines state that screening for syphilis for all pregnant women should be at the first prenatal visit. 1 In addition, the Centers for Disease Control and Prevention guidelines state that for pregnant women living in communities and populations in which syphilis prevalence is high including women at high risk for infection, syphilis testing should be repeated in the third trimester at 28 to 32 weeks and again at delivery. 1 In the Michigan Department of Health and Human Services’ guidelines for screening for syphilis during pregnancy, it states that all women should be screened for syphilis in the first trimester and at 28 weeks and at delivery.…”

“…1 Repeat long-bone radiographs were done 2 months after completing treatment and showed complete resolution of bone findings (Figures 1B and 2B). Repeat RPR titer was done 2 months after treatment, which showed a titer of 1:8, which is greater than a 4-fold decrease from the initial titer of 1:128, indicative of successful response to treatment.…”

Care-Seeking Behavior After Notification Among Young Women With Recurrent Sexually Transmitted Infections After Pelvic Inflammatory Disease

“…(5,6) Standard care for mild-to-moderate PID is outpatient treatment with a 72 hour follow-up. (6,7) However, follow up rates after PID diagnosis are low; less than one-quarter of adolescents with PID complete the CDC recommended 72 hour follow-up after a PID diagnosis. (8) Moreover, there is no data examining clinical follow-up rates for high-risk adolescents diagnosed with recurrent STIs after PID.…”

Emergence of fluoroquinolone-resistant Neisseria gonorrhoeae in São Paulo, Brazil

“…In response to the emergence of penicillinase-producing N. gonorrhoeae, N. gonorrhoeae with plasmid-mediated tetracycline resistance and N. gonorrhoeae with chromosomally mediated resistance to penicillin and/or tetracycline, the Centers for Disease Control and Prevention (CDC) has advocated the use of expanded-generation cephalosporins or fluoroquinolones as first-line therapy for uncomplicated gonorrhea (4,19). However, strains exhibiting decreased susceptibility to ciprofloxacin have been reported from many countries; strains exhibiting clinically significant resistance to CDC recommended doses of ciprofloxacin (500 mg orally, single-dose) or ofloxacin (400 mg, single-dose) have been reported from Asia, Australia, United Kingdom, United States and Canada (5,11,(14)(15)(16)(17).…”

“…Tel. : (19) 3289-4107. E-mail: pvelho@unicamp.br 7.7% in 1995 to 24% in 1996; in Singapore, it increased from 0.3% in 1993 to 3.5% in 1996; and in Australia it increased from 0.1% in 1992 to 2.6% in 1996 (9).…”