We present significant upgrades to the Visible Aperture-Masking Polarimetric Imager/Interferometer for Resolving Exoplanetary Signatures (VAMPIRES) instrument, a visible-light (600–800 nm) high-contrast imaging polarimeter integrated within SCExAO on the Subaru telescope. Key enhancements include new qCMOS detectors, coronagraphs, polarization optics, and a multiband imaging mode, improving sensitivity, resolution, and efficiency. These upgrades position VAMPIRES as a powerful tool for studying sub-stellar companions, accreting protoplanets, circumstellar disks, stellar jets, stellar mass-loss shells, and solar system objects. The instrument achieves angular resolutions from 17 to 21 mas and Strehl ratios up to 60%, with 5σ contrast limits of 10−4 at 0.″1 to 10−6 beyond 0.″5. We demonstrate these capabilities through spectro-polarimetric coronagraphic imaging of the HD 169142 circumstellar disk, ADI+SDI imaging of the sub-stellar companion HD 1160B, narrowband Hα imaging of the R Aqr emission nebula, and spectro-polarimetric imaging of Neptune.