The 6-Minute Walk Test predicts long-term physical improvement among intensive care unit survivors: a prospective cohort study

Rosa, Régis Goulart; Dietrich, Camila; Valle, Enio Luiz Tschiedel do; Souza, Denise de; Tagliari, Luciana Vilela; Mattioni, Mariana; Tonietto, Túlio Frederico; Rosa, Rosa da; Barbosa, Mirceli Goulart; Lovatel, Gisele Agustini; Lago, Pedro Dal; Oliveira, Eubrando Silvestre; Sganzerla, Daniel; Andrade, Juliana M S; Berto, Paula Pinheiro; Cardoso, Paulo Ricardo Cerveira; Sanchez, Evelin Carneiro; Falavigna, Maicon; Maccari, Juçara Gasparetto; Rech, Gabriela Soares; Robinson, Caroline Cabral; Schneider, Daniel; León, Patricia de; Biason, Livia; Teixeira, Cassiano

doi:10.5935/0103-507x.20210056

Cited by 5 publications

(4 citation statements)

References 48 publications

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“…However, we acknowledge that we have not performed a detailed cardiovascular evaluation that might have depicted differences in 6MWD performance, and it is a limitation of our study. Previous studies [17] have shown that 6MWD 4 months after ICU discharge in COVID-19 patients is significantly impaired compared to healthy subjects [36,37]. Other studies have shown that exercise capacity may be impaired 1 year after discharge [28,29,38].…”

Section: Discussionmentioning

confidence: 99%

Quality of Life, Family Support, Spirometry, and 6-Minute Walking Distance Differences between COVID-19 and Non-COVID-19 Intensive Care Unit Patients in One Year Following Hospital Discharge

Avgeri,

Mantzarlis,

Gerovasileiou

et al. 2024

Healthcare

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Background: Critically ill patients after Intensive Care Unit (ICU) discharge may present disability in their cognitive and physical functions. Objectives: To investigate the quality of life (QoL) of both COVID-19 and non-COVID-19 patients following ICU discharge, lung function, and physical performance of participants. Methods: This study was prospective and conducted between 2020 and 2021 in the “X” hospital. If patients were Mechanically-Ventilated (MV) > 48 h, they were included. Results: Fifty COVID-19 and seventy-two non-COVID-19 participants were included in this study. The mean (SD) of the total SF-36 scores at COVID-19 patients at hospital discharge and 3 and 12 months were 46.5 (14.5), 68.6 (17.8), and 82.3 (8.9) (p < 0.05), while non-COVID-19 participants were 48.5 (12.1), 72.2 (9.9), and 82.7 (5.4) (p < 0.05). The forced expiratory volume in one second (FEV1) and 6-minute walking distance (6MWD) were assessed at 3 and 12 months and significantly improved over 12 months. Conclusion: The QoL of COVID-19 patients improved significantly over time as FEV1 and 6MWD.

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Section: Discussionmentioning

confidence: 99%

Quality of Life, Family Support, Spirometry, and 6-Minute Walking Distance Differences between COVID-19 and Non-COVID-19 Intensive Care Unit Patients in One Year Following Hospital Discharge

Avgeri,

Mantzarlis,

Gerovasileiou

et al. 2024

Healthcare

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“…In the present investigation, we assessed patients’ physical performances and lung function following the ICU in terms of the 6MWT distance and spirometry. Previous studies have suggested that ICU patients who survived four months after discharge had significantly worse outcomes than the healthy population [ 27 , 28 ]. The 6MWT performance of ICU patients has been studied in severe respiratory disease; ARDS survivors presented significantly reduced 6-min walking distances at six months and one year follow-up [ 29 , 30 , 31 ].…”

Section: Discussionmentioning

confidence: 99%

Quality of Life and Family Support in Critically Ill Patients following ICU Discharge

et al. 2023

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Background: Following discharge from the intensive care unit (ICU), critically ill patients may present cognitive dysfunction and physical disability. Objectives: To investigate the quality of life (QoL) of patients following discharge from ICU, physical performance and lung function and to assess the role of support by family members and friends. Methods: This prospective study was conducted in the University Hospital of Larissa Greece between 2020 and 2021. Patients hospitalized at the ICU for at least 48 h were included and assessed at hospital discharge, at 3 and at 12 months later. The research implements of the study were a dedicated questionnaire and the SF-36 health questionnaire for the appraisal of the QoL. Lung function changes were assessed by spirometry and physical performance by the 6-min walking test (6MWT). Results: One hundred and forty-three participants were included in the study. The mean (SD) of the physical and mental health SF-36 scores at hospital discharge, 3 and 12 months were 27.32 (19.59), 40.97 (26.34) and 50.78 (28.26) (p < 0.0001) and 42.93 (17.00), 55.19 (23.04) and 62.24 (23.66), (p < 0.0001), respectively. The forced expiratory volume in one second and 6MWT significantly improved over 12 months. Patients who were supported by two or more family members or patients who were visited by their friends >3 times/week presented better scores in the physical and mental SF36 domains at 12 months. Conclusion: This study shows that the quality of life of Greek patients who were discharged from the ICU can be positively affected both by the support they receive from their family environment and friends.

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“…Nine studies reported data for the 6MWT [13,28,30,31,36,38,39,48]. No studies in our review tested the reliability of the 6MWT.…”

Section: -Min Walk Test (6mwt)mentioning

confidence: 96%

“…There was a high certainty of evidence supporting sufficient construct validity. Two studies validated the GLIM against the Subjective Global Assessment (SGA) demonstrating a high level of precision (AUC 0.85-0.93) and agreement (Kappa 0.85) [48,49]. The GLIM at ICU admission was predictive of ICU mortality and hospital length of stay [73].…”

Section: Nutritional Status Global Leadership Initiative On Malnutrit...mentioning

confidence: 97%

A systematic review and meta-analysis of the clinimetric properties of the core outcome measurement instruments for clinical effectiveness trials of nutritional and metabolic interventions in critical illness (CONCISE)

Davies,

Kelly,

van Gassel

et al. 2023

Crit Care

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Background CONCISE is an internationally agreed minimum set of outcomes for use in nutritional and metabolic clinical research in critically ill adults. Clinicians and researchers need to be aware of the clinimetric properties of these instruments and understand any limitations to ensure valid and reliable research. This systematic review and meta-analysis were undertaken to evaluate the clinimetric properties of the measurement instruments identified in CONCISE. Methods Four electronic databases were searched from inception to December 2022 (MEDLINE via Ovid, EMBASE via Ovid, CINAHL via Healthcare Databases Advanced Search, CENTRAL via Cochrane). Studies were included if they examined at least one clinimetric property of a CONCISE measurement instrument or recognised variation in adults ≥ 18 years with critical illness or recovering from critical illness in any language. The COnsensus-based Standards for the selection of health Measurement INstruments (COSMIN) checklist for systematic reviews of Patient-Reported Outcome Measures was used. The Preferred Reporting Items for Systematic Reviews and Meta-Analyses were used in line with COSMIN guidance. The COSMIN checklist was used to evaluate the risk of bias and the quality of clinimetric properties. Overall certainty of the evidence was rated using a modified Grading of Recommendations, Assessment, Development and Evaluation approach. Narrative synthesis was performed and where possible, meta-analysis was conducted. Results A total of 4316 studies were screened. Forty-seven were included in the review, reporting data for 12308 participants. The Short Form-36 Questionnaire (Physical Component Score and Physical Functioning), sit-to-stand test, 6-m walk test and Barthel Index had the strongest clinimetric properties and certainty of evidence. The Short Physical Performance Battery, Katz Index and handgrip strength had less favourable results. There was limited data for Lawson Instrumental Activities of Daily Living and the Global Leadership Initiative on Malnutrition criteria. The risk of bias ranged from inadequate to very good. The certainty of the evidence ranged from very low to high. Conclusions Variable evidence exists to support the clinimetric properties of the CONCISE measurement instruments. We suggest using this review alongside CONCISE to guide outcome selection for future trials of nutrition and metabolic interventions in critical illness. Trial registration : PROSPERO (CRD42023438187). Registered 21/06/2023.

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The 6-Minute Walk Test predicts long-term physical improvement among intensive care unit survivors: a prospective cohort study

Cited by 5 publications

References 48 publications

Quality of Life, Family Support, Spirometry, and 6-Minute Walking Distance Differences between COVID-19 and Non-COVID-19 Intensive Care Unit Patients in One Year Following Hospital Discharge

Quality of Life, Family Support, Spirometry, and 6-Minute Walking Distance Differences between COVID-19 and Non-COVID-19 Intensive Care Unit Patients in One Year Following Hospital Discharge

Quality of Life and Family Support in Critically Ill Patients following ICU Discharge

A systematic review and meta-analysis of the clinimetric properties of the core outcome measurement instruments for clinical effectiveness trials of nutritional and metabolic interventions in critical illness (CONCISE)

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