2010
DOI: 10.1111/j.1476-5381.2010.00789.x
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The abuse of diuretics as performance‐enhancing drugs and masking agents in sport doping: pharmacology, toxicology and analysis

Abstract: Diuretics are drugs that increase the rate of urine flow and sodium excretion to adjust the volume and composition of body fluids. There are several major categories of this drug class and the compounds vary greatly in structure, physicochemical properties, effects on urinary composition and renal haemodynamics, and site and mechanism of action. Diuretics are often abused by athletes to excrete water for rapid weight loss and to mask the presence of other banned substances. Because of their abuse by athletes, … Show more

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Cited by 120 publications
(96 citation statements)
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“…Sometimes the creatinine level is elevated [4,35]. TD abuse is often found in cases of eating disorders, weight-loss attempts and sport doping [30][31][32][33][34]36].…”
Section: Discussionmentioning
confidence: 99%
“…Sometimes the creatinine level is elevated [4,35]. TD abuse is often found in cases of eating disorders, weight-loss attempts and sport doping [30][31][32][33][34]36].…”
Section: Discussionmentioning
confidence: 99%
“…Since 1988, the use of diuretics in sports is prohibited (Cadwallader, de la Torre, Tieri, Botrè, 2010), both during and out of competition. This is due to the fact that athletes use diuretics for many reasons: to reduce their body weight or to limit the excessive water retention caused by the abuse of anabolic steroids and to mask the presence of banned substances in urine.…”
Section: Diureticsmentioning
confidence: 99%
“…Therefore, when urine samples are taken to carry out the doping test, the research of these substances is always carried out (Thevis, Schänzer 2005). However, if the athlete is suffering from a disease that requires treatment with diuretics, the doctor may request the their use for therapeutic purposes (TUE) to WADA and therefore to be considered negative for anti-doping controls (Cadwallader et al 2010).…”
Section: Diureticsmentioning
confidence: 99%
“…76 The use of diuretics is banned both in and out of competition and diuretics are routinely screened for by antidoping laboratories. 76 …”
Section: Diuretic Abusementioning
confidence: 99%