The Accuracy of PillCam ESO Capsule Endoscopy Versus Conventional Upper Endoscopy for the Diagnosis of Esophageal Varices: A Prospective Three-Center Pilot Study

Eisen, Glenn M.; Eliakim, Rami; Zaman, Atif; Schwartz, Jonathan M.; Faigel, Douglas O.; Rondonotti, Emanuele; Villa, Federica; Weizman, E.; Yassin, Kamel; DeFranchis, Roberto

doi:10.1055/s-2005-921189

Cited by 157 publications

(87 citation statements)

References 10 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…A procedure that may replace EGD is esophageal capsule endoscopy. Two recent pilot studies show that capsule endoscopy is a safe and well-tolerated way to diagnose esophageal varices, 47,48 although its sensitivity remains to be established. Thus, capsule endoscopy may play a future role in screening for esophageal varices if additional larger studies support its use.…”

Section: Diagnosis Of Varices and Variceal Hemorrhagementioning

confidence: 99%

Prevention and management of gastroesophageal varices and variceal hemorrhage in cirrhosis

et al. 2007

View full text Add to dashboard Cite

Section: Diagnosis Of Varices and Variceal Hemorrhagementioning

confidence: 99%

Prevention and management of gastroesophageal varices and variceal hemorrhage in cirrhosis

et al. 2007

View full text Add to dashboard Cite

“…Fifty-one articles were excluded after review of the titles and abstracts, leaving 30 articles for detailed evaluation by two independent reviewers. Of these, five met our inclusion criteria [10,[14][15][16][17] . Two studies were identified by hand search in DDW 2008 meeting abstracts and reference lists respectively [18,19] .…”

Section: Resultsmentioning

confidence: 99%

“…Recent years, a number of studies have been performed for evaluating CE in diagnosing esophageal disease, especially for Barrett's esophagus and esophageal varices, and the results varied [8][9][10] . If CE is a definitive diagnostic tool for esophageal varices, it is necessary to evaluate whether CE is sufficiently accurate for this purpose.…”

Section: Introductionmentioning

confidence: 99%

“…ECE provides a potentially less invasive diagnostic alternative in evaluating diseases of the esophagus such as esophageal varices, Barrett's esophagus, and gastroesophageal reflux disease (GERD)/erosive esophagitis [8][9][10][11] . Furthermore, Ramirez et al [12] attached a string to SBCE in the middle of the device which can allow the capsule to move up and down in the esophagus by swallowing the capsule and pulling the string.…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Meta-analysis of capsule endoscopy in patients diagnosed or suspected with esophageal varices

Gao²,

Liao³

et al. 2009

WJG

View full text Add to dashboard Cite

AIM:To review the literature on capsule endoscopy (CE) for detecting esophageal varices using conventional esophagogastroduodenoscopy (EGD) as the standard. METHODS:A strict literature search of studies comparing the yield of CE and EGD in patients diagnosed or suspected as having esophageal varices was conducted by both computer search and manual search. Data were extracted to estimate the pooled diagnostic sensitivity and specificity. RESULTS:There were seven studies appropriate for meta-analysis in our study, involving 446 patients. The pooled sensitivity and specificity of CE for detecting esophageal varices were 85.8% and 80.5%, respectively. In subgroup analysis, the pooled sensitivity and specificity were 82.7% and 54.8% in screened patients, and 87.3% and 84.7% in the screened/ patients under surveillance, respectively.CONCLUSION: CE appears to have acceptable sensitivity and specificity in detecting esophageal varices. However, data are insufficient to determine the accurate diagnostic value of CE in the screen/ surveillance of patients alone.

show abstract

“…Modalities such as platelet count, platelet count to spleen diameter ratio, and fibroscan could have a good predictive value but need confirmation by further studies. Capsule endoscopy has emerged as a new diagnostic tool and is considered safe and well tolerated, although its sensitivity remains to be established [15,16]. Its role for screening varices needs further studies.…”

Section: Definitions Of Varices and Variceal Bleed Prophylaxismentioning

confidence: 99%

Primary prophylaxis of gastroesophageal variceal bleeding: consensus recommendations of the Asian Pacific Association for the Study of the Liver

et al. 2008

View full text Add to dashboard Cite

The Asian Pacific Association for the Study of the Liver (APASL) set up a Working Party on Portal Hypertension in 2002, with a mandate to develop consensus guidelines on various clinical aspects of portal hypertension relevant to disease patterns and clinical practice in the Asia-Pacific region. Variceal bleeding is a consequence of portal hypertension, which, in turn, is the major complication of liver cirrhosis. Primary prophylaxis to prevent the first bleed from varices is one of the most important strategies for reducing the mortality in cirrhotic patients. Experts predominantly from the Asia-Pacific region were requested to identify the different aspects of primary prophylaxis and develop the consensus guidelines. The APASL Working Party on Portal Hypertension evaluated the various therapies that have been used for the prevention of first variceal bleeding. A 2-day meeting was held on January 12 and 13, 2007, at New Delhi, India, to discuss and finalize the consensus statements. Only those statements that were unanimously approved by the experts were accepted. These statements were circulated to all the experts and were subsequently presented at the annual conference of the APASL at Kyoto, Japan, in March 2007.

show abstract

The Accuracy of PillCam ESO Capsule Endoscopy Versus Conventional Upper Endoscopy for the Diagnosis of Esophageal Varices: A Prospective Three-Center Pilot Study

Abstract: In a high-prevalence population, PillCam ESO may represent an accurate noninvasive alternative to EGD for the detection of esophageal varices and portal hypertensive gastropathy. A large-scale trial is underway to validate and expand these findings.

Cited by 157 publications

References 10 publications

Prevention and management of gastroesophageal varices and variceal hemorrhage in cirrhosis

Prevention and management of gastroesophageal varices and variceal hemorrhage in cirrhosis

Meta-analysis of capsule endoscopy in patients diagnosed or suspected with esophageal varices

Primary prophylaxis of gastroesophageal variceal bleeding: consensus recommendations of the Asian Pacific Association for the Study of the Liver

Contact Info

Product

Resources

About