“…'Î t will be recalled that, if frogs are kept in water, the injection of posterior-lobe extract promotes the transfer of water through the skin (and perhaps its retention), so that the body-weight increases. In confirmation of earlier work, Oldham (1936) found that the oxytocic principle is 2.5-5.0 times as efl^ective as the vasopressor hormone in causing this efi^ect. The chromatosome-dispersing hormone probably is not a factor (Jones and Steggerda, 1935;Oldham, 1936).…”