In this paper, we study a fully non-local reaction-diffusion equation which is non-local both in time and space. We apply subordination principles to construct the fundamental solutions of this problem, which we use to find a representation of the mild solutions. Moreover, using techniques of Harmonic Analysis and Fourier Multipliers, we obtain the temporal decay rates for the mild solutions.1991 Mathematics Subject Classification. Primary: 35B40, 35R11, 35E05; Secondary: 42A45. Key words and phrases. Non-local partial differential equations, large-time behavior of solutions, fundamental solutions and subordination methods.