The activity of camel milk to treated immunity changes that induced by Giardia lamblia in male rats

Ali, Abeer Abbas; Al-Attar, Shahad Abbas Ali

doi:10.36295/asro.2020.23415

Cited by 4 publications

(4 citation statements)

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“…The therapeutic effects of camel milk are known in different parts of the world due to the presence of bioactive agents in the milk. It has been used for the treatment of different diseases, such as dropsy, jaundice, tuberculosis, kala‐azar (Ali & Al‐Attar, 2020) and anemia (Abdurahman, 2018). Furthermore, it has been demonstrated that camel milk is very effective in the treatment of liver disorders to normalize their functions (Darwish et al., 2012).…”

Section: Introductionmentioning

confidence: 99%

Camel milk as an alternative treatment regimen for diabetes therapy

Hussain

Wattoo

et al. 2021

Food Science & Nutrition

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Camel milk is a valuable source of nutrition with a wide range of therapeutic effects. Its unique composition helps to regulate the blood glucose level. The current study is aimed to evaluate the antidiabetic and hepatoprotective effects, as well as lipid profile restoration of camel milk in the diabetic mouse model. This innovative study evaluates the therapeutic effects of camel milk in diabetic mice by simultaneous measurement of blood glucose, HbA1c, ALT, AST, TG, cholesterol, and histopathological studies. The results showed that camel milk has significantly reduced blood glucose, HbA1c (p < .001), aspartate transaminase (AST), alanine transaminase (ALT) (p < .01), triglyceride (TG), and cholesterol (p < .01), compared to that in the diabetic control group. Also, the therapeutic effects of camel milk were completely comparable with the antidiabetic drug glibenclamide. The results of this study suggest that camel milk could be used as a proper alternative treatment regimen for diabetes therapy.

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Section: Introductionmentioning

confidence: 99%

Camel milk as an alternative treatment regimen for diabetes therapy

Hussain

Wattoo

et al. 2021

Food Science & Nutrition

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“…Camel milk has gained recognition for its distinctive therapeutic and nutritional benefits in recent scientific investigations. Previous studies have demonstrated its effectiveness in treating various conditions such as dropsy, jaundice, tuberculosis, kala-azar, and anemia. , Furthermore, scientific evidence supports the anticancer, antiallergic, and antidiabetic effects of camel milk. − Camel milk is rich in vitamins (particularly A, B2, Chighest concentration, and E) and minerals (including Na, K, Fe, Cu, Zn, and Mg), as well as immunoglobulins (G and A). However, it is not as abundant in sugar, proteins, or cholesterol. , The therapeutic impact of camel milk on Langerhans islet cells, mediated by its immunoglobulins, has led to its use in the treatment of diabetes mellitus in certain regions of Asia, the Middle East, and Africa .…”

Section: Introductionmentioning

confidence: 97%

“…Previous studies have demonstrated its effectiveness in treating various conditions such as dropsy, jaundice, tuberculosis, kala-azar, and anemia. 25,26 Furthermore, scientific evidence supports the anticancer, antiallergic, and antidiabetic effects of camel milk. 27−29 Camel milk is rich in vitamins (particularly A, B2, C�highest concentration, and E) and minerals (including Na, K, Fe, Cu, Zn, and Mg), as well as immunoglobulins (G and A).…”

Section: ■ Introductionmentioning

confidence: 97%

Comparative Attenuating Impact of Camel Milk and Insulin in Streptozotocin-Induced Diabetic Albino Rats

Raj,

Shuklan,

Madan

et al. 2023

ACS Omega

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In this study, albino Wistar rats that have developed diabetes as a result of the drug streptozotocin (STZ) were treated with camel milk and insulin. For this, 36 rats were divided into six different (n = 6) groups: control, control + camel milk, diabetic control, insulin, camel milk, and combined camel milk + insulin. A 50 mg/kg intraperitoneal injection of STZ was used to induce diabetes. Rats with blood glucose levels exceeding 250 mg/dL after the induction of diabetes were taken into consideration for the study. The diabetic rats were treated with camel milk (50 mL/rat/day), insulin (6 units kg −1 b•wt/ day), or their combination daily for 30 days. Throughout the course of the study, the rats' glucose levels and body weight were checked. In the diabetic control rats, a reduction in body weight and hyperglycemic condition was seen. Improvements in glycemic levels and weight gain were seen in the camel milk, insulin, and combined treatment groups compared to the diabetic control group; however, the combined treated group did not show the same degree of improvement as the alone treated group. Hematological changes in the diabetic control group included reductions in lymphocytes, platelets, total leukocyte count (TLC), and red blood cell (RBC) indices (mean corpuscular volume (MCV), mean corpuscular hemoglobin (MCH), packed cell volume (PCV), and mean cell hemoglobin concentration (MCHC)). Each group that got insulin and camel milk separately and combined showed improvement in these changes. The liver, kidney, and pancreas in the diabetic control group had worsened morphological alterations. These histopathological alternations were significantly improved in the treatment groups. Hence, this study demonstrates the antidiabetic effects of camel milk in comparison to insulin. These findings highlight the potential of camel milk as an alternative therapy for diabetes, although further research is warranted to fully understand its mechanisms of action and long-term effects.

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“…The therapeutic property of camel's milk is well-known globally. Traditionally, it has been used for the management of many illnesses such as tuberculosis, jaundice, and kala-azar [1,6]. IgG and Lactoferrin in camel's milk can suppress the replication of hepatitis C and B viruses.…”

Section: Introductionmentioning

confidence: 99%

The Impact of Camel Milk Consumption on Modulation and Abundance of Gut Microbiota

Najjar

Almugadam

Asseri

et al. 2023

J. Pharm. Res. Int.

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Previous studies explored the nutritional, anti-bacterial, anti-fungal, anti-viral, anti-inflammatory, antioxidant, and anti-tumor properties of camel milk but the precise mechanisms by which camel milk induces these health benefits remain to be investigated. The study aimed to evaluate the effect of camel milk on the diversity and abundance of gut microbiota. 15 male subjects were enrolled in the cohort (follow-up) study. To evaluate the impact of camel milk on gut microbiota, each subject received 330ml of camel milk four times/every week for one month. A stool sample was collected from each subject before starting milk feeding and after one month of the milk diet. Each stool sample was subjected to bacterial DNA extraction by using the commercial Kit. Next, all DNA samples were subjected to 16s rRNA sequencing. The observed species and Chao1 indices are higher after (Group B) camel milk consumption, P˃0.05. Shannon was also higher after camel milk consumption (Group B) but it is not significant. The shift in gut microbiota following milk consumption was characterized by a significant increase in Methanobrevibacter, Subdoligranulum, and bacillus. Notably, smoking significantly decrease the abundance of Bifidobacterium, and excise improves the abundance of Lachnospiraceae, P˂0.05. On correlation, Bifidobacterium and several beneficial bacteria were negatively correlated with age. The study provides insight concerning the effect of camel’s milk on gut microbiota, which is key in understanding the impact of camel’s milk on health.

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The activity of camel milk to treated immunity changes that induced by Giardia lamblia in male rats

Cited by 4 publications

References 0 publications

Camel milk as an alternative treatment regimen for diabetes therapy

Camel milk as an alternative treatment regimen for diabetes therapy

Comparative Attenuating Impact of Camel Milk and Insulin in Streptozotocin-Induced Diabetic Albino Rats

The Impact of Camel Milk Consumption on Modulation and Abundance of Gut Microbiota

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