2023
DOI: 10.14710/jbtr.v9i2.17290
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The Activity of Liposome-Parijoto Formula Through p53 Expression in HepG2 Cell Line

Widyandani Sasikirana,
Ragil Setia Dianingati,
Khairul Anam
et al.

Abstract: Parijoto, one of Melastomaceae family, has been known to have cytotoxic activity in HepG2, a hepatocellular cancer cell line, but with low activity. However, the ethyl acetate fraction of Parijoto gave the highest antioxidant and cytotoxic activity in 4T1. Then, purification and liposome formulation need to be carried out to increase the activity of Parijoto extract.  Objective: This research aimed to study the cytotoxic activity and molecular mechanism of LEA (Liposom-Ethyl Acetate of Parijoto Fraction) in He… Show more

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