The added value of a surveillance human biomonitoring program: The case of FLEHS in Flanders (Belgium)

Reynders, Hans; Colles, Ann; Morrens, Bert; Mampaey, Maja; Coertjens, Dries; Koppen, Gudrun; Schoeters, Greet; Loots, Ilse; Chovanova, Hana; Winderickx, Wim; Campenhout, Karen Van

doi:10.1016/j.ijheh.2016.09.013

Cited by 17 publications

(10 citation statements)

References 46 publications

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“…Following the principles of an analytical deliberative approach, phases of desk research and expert consultation were alternated with local deliberation, recognizing the importance of both academic and local knowledge [ 36 ]. This approach in the context of the FLEHS studies was previously described [ 37 , 38 ]. In addition, a focus group with citizens was organized to further explore support for policy options.…”

Section: Methodsmentioning

confidence: 99%

Human Biomonitoring Data Enables Evidence-Informed Policy to Reduce Internal Exposure to Persistent Organic Compounds: A Case Study

Colles

Coertjens

Morrens

et al. 2021

IJERPH

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Human biomonitoring (HBM) monitors levels of environmental pollutants in human samples, which often is a topic of concern for residents near industrially contaminated sites (ICSs). Around an ICS area in Menen (Belgium), including a (former) municipal waste incinerator and a metal recovery plant, increasing environmental concentrations of dioxins and polychlorinated biphenyls (PCBs) were observed, causing growing concern among residents and authorities. The local community succeeded in convincing the responsible authorities to investigate the problem and offer research funding. Persistent organic pollutants (POPs) were measured in two consecutive HBM studies (2002–2006 and 2010–2011), in the context of the Flemish Environment and Health Study (FLEHS), as well as in soil and locally produced food. Meanwhile, local authorities discouraged consumption of locally produced food in a delineated area of higher exposure risk. Ultimately, HBM and environmental data enabled tailored dietary recommendations. This article demonstrates the usefulness of HBM in documenting the body burdens of residents near the ICS, identifying exposure routes, evaluating remediating actions and providing information for tailored policy strategies aiding to further exposure reduction. It also highlights the role of the local stakeholders as an example of community-based participatory research and how such an approach can create societal support for research and policy.

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Section: Methodsmentioning

confidence: 99%

Human Biomonitoring Data Enables Evidence-Informed Policy to Reduce Internal Exposure to Persistent Organic Compounds: A Case Study

Colles

Coertjens

Morrens

et al. 2021

IJERPH

Self Cite

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“…In studies with a high risk of bias that could potentially be resolved by obtaining additional information, the authors were contacted via corresponding email addresses on the publication, on more than one occasion over a period of several months, to obtain that information. Contacting the authors was performed according to previously published strategy 16 . If the authors did not respond, or the risk of bias remained high after additional information had been obtained, the data point at question was excluded from further analysis.…”

Section: Methodsmentioning

confidence: 99%

“…Contacting the authors was performed according to previously published strategy. 16 If the authors did not respond, or the risk of bias remained high after additional information had been obtained, the data point at question was excluded from further analysis.…”

Section: Handling Missing Datamentioning

confidence: 99%

Planned oocyte cryopreservation (Planned OC): systematic review and meta‐analysis of cost‐efficiency and patients’ perspective

Weizman

Baram

Montbriand

et al. 2020

BJOG

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Background Advances in vitrification techniques have enabled planned oocyte cryopreservation (‘Planned OC’). Objectives To explore the cost‐efficiency and utilisation of planned OC, as well as patients’ perspectives on the process. Search strategy A systematic search in PubMed/MEDLINE, Embase, Cochrane Database and PsychINFO, for all relevant studies published between January 2007 and December 2019. Selection criteria The protocol followed PRISMA guidelines in PECO format, and was registered with PROSPERO. Data collection and analysis Two independent reviewers evaluated all manuscripts for inclusion eligibility. Authors were contacted for missing data. Included studies were assessed for risk of bias and for heterogeneity. Weighted effects were measured and plotted. Main results The search yielded 12 545 records, of which 43 were included. Planned OC is cost‐efficient at 35, assuming 60% utilisation; and at 37 assuming utilising donor sperm when necessary. At 38 it is cost‐efficient to defer planned OC in favour of undergoing 2 IVF cycles. Currently, utilisation of banked‐oocytes within 22–58 months, is up to 15%. Nine percent of warmed banked oocytes result in life births. Online resources and treating physicians are equally important sources of information regarding planned OC. Most patients think planned OC is ideal before age 35 and are not fully aware of what the process entails and tend to overestimate the success rates. The main barrier to wider endorsement of planned OC is being wary of potential health implications or of limited success. Conclusion Planned OC is an adequate method for preserving fertility. However, knowledge gaps result in under‐utilisation leading to reduced cost‐efficiency. Tweetable abstract Identifying facilitators and barriers for wider adoption of banking oocytes can enhance the cost‐efficiency of this modality.

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“…Detailed information about exposure to chemicals, including EDs, exist in specific countries such as Belgium [236], France [237], Germany, where compounds such as phthalates have been monitored for a long time [124] and Portugal [238]……”

Section: In Human Populations -Data Available In Specific Countriesmentioning

confidence: 99%

Mikroplastik: vom Tiegel auf den Teller

Saha¹

2021

Dtsch Dermatolog

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This study, commissioned by the PETI Committee of the European Parliament, presents the scientific knowledge regarding the health effects of endocrine disruptors, a class of hazards recognized in EU regulation since 1999. This report reviews the scientific evidence regarding the concept of endocrine disruption, the extent of exposure, associated health effects and costs. The existing relevant EU regulations are discussed and recommendations made to better protect human health. ABOUT THE PUBLICATIONThis research paper was requested by the European Parliament's Committee on Petitions and commissioned, overseen and published by the Policy Department for Citizen's Rights and Constitutional Affairs.Policy Departments provide independent expertise, both in-house and externally, to support European Parliament committees and other parliamentary bodies in shaping legislation and exercising democratic scrutiny over EU external and internal policies.

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The added value of a surveillance human biomonitoring program: The case of FLEHS in Flanders (Belgium)

Cited by 17 publications

References 46 publications

Human Biomonitoring Data Enables Evidence-Informed Policy to Reduce Internal Exposure to Persistent Organic Compounds: A Case Study

Human Biomonitoring Data Enables Evidence-Informed Policy to Reduce Internal Exposure to Persistent Organic Compounds: A Case Study

Planned oocyte cryopreservation (Planned OC): systematic review and meta‐analysis of cost‐efficiency and patients’ perspective

Mikroplastik: vom Tiegel auf den Teller

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